Results 71 to 80 of about 29,714 (222)

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

Antipsychotics‐Induced Hyposalivation Mediated by Impaired Salivary Ca2+ Signaling

Oral Diseases, EarlyView.
ABSTRACT Objectives Antipsychotic‐induced salivary dysfunction such as hyposalivation is a prevalent clinical challenge that severely compromises oral health and quality of life. Although typical and atypical antipsychotics have their therapeutic target in the central nervous system, their direct molecular mechanisms within the salivary glands remain ...
Chaelin Chung, Soohyun Kim, Yoo‐Bin Kim, Hee‐Kyung Park, Se‐Young Choi   +4 more
wiley   +1 more source

Association between initial 30‐day cumulative clozapine dose and risk of agranulocytosis: A nationwide register‐based cohort study

Psychiatry and Clinical Neurosciences, EarlyView.
Aims Clozapine‐induced agranulocytosis (CIA) is traditionally considered an idiosyncratic, dose‐independent reaction. However, emerging evidence suggests that clozapine‐related inflammatory events may exhibit dose‐dependent characteristics, leading us to hypothesize that CIA risk may similarly relate to early cumulative exposure.
Yuki Kikuchi, Xue Li, Hiroshi Komatsu, Norio Yasui‐Furukori, Ken Inada, Hiroaki Tomita   +5 more
wiley   +1 more source

Characterizing social motivation deficits in treatment‐resistant schizophrenia: Evidence from social incentive performance

Psychiatry and Clinical Neurosciences, EarlyView.
Aim The Treatment‐Response‐and‐Resistance‐in‐Psychosis (TRRIP) criteria recognizes negative symptoms as defining features for treatment‐resistant schizophrenia (TRS). Social motivation refers to the desire to pursue social reward (and to avoid social punishment).
Simon S.Y. Lui, Jasmine W.S. Chan, Jason L.F. Chan, Kimi H.Y. Lam, Lok‐Yin Choi, Raisie W.K. Wong, Perry B.M. Leung, Na Zhan, Jason W.Y. Wong, Mindi W.Y. Chiu, Jenny P.H. Lam, Raymond C.K. Chan   +11 more
wiley   +1 more source

Of mice and men—The emerging oral–gut–brain axis of health and disease

Periodontology 2000, EarlyView.
Abstract Objectives Oral health's inextricable links to systemic health are highlighted by the emerging oral–gut–brain axis and other well‐known axes. There is growing evidence of a complex oral–gut–brain axis linking mouth and gut microbiomes with the central nervous system.
Yvonne L. Hernandez‐Kapila, Daniel J. Weisenberger   +1 more
wiley   +1 more source

COVID-19 disease outcomes in patients receiving clozapine versus other antipsychotics: a national study in Qatar

Frontiers in Psychiatry
BackgroundClozapine has immunomodulatory effects that raised concerns about its potential to exacerbate severe COVID-19. This study examines whether clozapine use is associated with worse COVID-19 outcomes in patients with schizophrenia.MethodsThis ...
Dalia Albahari, Oraib Abdalla, Shatha Mahmud Ismail Alqam, Mohammed Faisal Hamad Mohammed, Mohamed Ali Siddig Ahmed, Ovais Wadoo, Ovais Wadoo   +6 more
doaj   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

The Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil, Justin Shane Hooper, Seol‐Hee Kim, Parmvir K. Bahia, Nika Pavelkova, Sanjay S. Nair, Teresa S. Darcey, Karina V. Lurye, Meghana Madaram, Jailene Fiallo, Stephen H. Hadley, Thomas E. Taylor‐Clark   +11 more
wiley   +1 more source

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

The Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato, Lorenzo Santini, Raffaele Coppini, Eleonora Grandi   +3 more
wiley   +1 more source

Case series and Literature review – Clozapine Induced Transient Myocarditis. Clinical characteristics and outcomes

European Psychiatry
Introduction Clozapine is a second-generation atypical antipsychotic medication used in patients with treatment-refractory schizophrenia. Its use is limited due to its associated adverse effects, including myocarditis.
U. L. Anyeji, P. Bidkhanian
doaj   +1 more source