Results 71 to 80 of about 45,210 (266)

Effective and safe use of intramuscular clozapine in a patient presenting with catatonia and thrombocytopenia [PDF]

Clozapine is the most effective medication for the management of treatment-resistant schizophrenia and schizoaffective disorder, and its discontinuation can pose significant challenges in treatment.
Thapaliya, Suresh, Whiskey, Eromona, Firdosi, Mudasir   +2 more
core   +3 more sources

Retrospective evaluation of sociodemographic and clinical characteristics of patients with schizophrenia receiving clozapine monotherapy and clozapine combined with different antipsychotics

European Psychiatry
Introduction Schizophrenia is a chronic mental disorder and clozapine is an atypical antipsychotic that can be used in treatment-resistant schizophrenia patients.
E. Yıldız, S. N. İspir, H. R. Demirel, S. Odabaş Ünal, M. Aydın   +4 more
doaj   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

Clozapine-induced insulin-resistant hyperglycemia in a diabetic patient

Indian Journal of Psychological Medicine, 2018
Clozapine is superior to all other antipsychotics in treatment-resistant schizophrenia. However, metabolic side effects are common while treating patients with clozapine.
Vijay Chathoth, Parthasarathy Ramamurthy, Susan Solomon   +2 more
doaj   +1 more source

Continuous Intrajejunal Levodopa–Carbidopa Infusion in Parkinson's Disease Associated with 22q11.2 Deletion Syndrome: A Case Series

Movement Disorders Clinical Practice, EarlyView.
Abstract Background 22q11.2 deletion syndrome (22q11DS) is a multisystem genetic disorder associated with a significantly increased risk of early‐onset Parkinson's disease (EOPD). Management is challenging because psychiatric and cognitive comorbidities often limit advanced therapies such as deep brain stimulation (DBS). Cases We report 2 patients with
Valle Victor Andrés, Jardel Amory, Hopes Lucie, Clément Guillemette, Lambert Laetitia, Becker Aurélie, Dexheimer Mylène, Bonnet Céline, Frismand Solène, Renaud Mathilde, Puisieux Salomé   +10 more
wiley   +1 more source

Loxapine and Cyproheptadine Combined Limit Clozapine Rebound Psychosis and May Also Predict Clozapine Response

Case Reports in Psychiatry, 2016
Clozapine has been consistently shown to be superior to other antipsychotics in the treatment of psychosis. However, clozapine usage has been limited due to required routine blood monitoring and the potential for life threatening side effects.
Lila Aboueid, Richard H. McCarthy
doaj   +1 more source

Dose-dependent clozapine-induced skin picking and self-injurious behaviour in treatment-resistant schizophrenia

Sri Lanka Journal of Medicine, 2020
Clozapine is a second-generation antipsychotic used for treatment-resistant schizophrenia. Obsessive-compulsive symptoms induced by clozapine is a known entity.
Layani C. Rathnayake, Miyuru Chandradasa, Jayan Mendis   +2 more
doaj   +1 more source

Patients Receiving 100 or More Electroconvulsive Therapy Treatments in a Nationwide Cohort

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Very high cumulative exposure to electroconvulsive therapy (ECT) has primarily been described in individual case reports. We examined cumulative ECT exposure in a nationwide Japanese claims database to characterize patients receiving very high numbers of treatments.
Masahiro Hata, Yuki Miyazaki, Shun Takahashi   +2 more
wiley   +1 more source

Clozapine in pregnancy

Indian Journal of Psychiatry, 2006
This report describes the case of a woman with treatment-resistant schizophrenia who became pregnant while being treated successfully with clozapine. Possible risks associated with continuation of clozapine during pregnancy are discussed.
openaire   +3 more sources

Absolute neutrophil count and adverse drug reaction monitoring during clozapine treatment: consensus guidelines from a global Delphi panel [PDF]

Despite its superior effectiveness for treatment-resistant schizophrenia, clozapine has a high burden of adverse drug reactions (ADRs), which require monitoring and treatment.
Northwood, K, Pillinger, T, Siskind, D, Breznoscakova, D, Kawashima, H, Correll, C., Howes, O.D., Kane, J.M., Myles, N., Venkatasubramanian, G, Keating, D, Selten, J, Murray, G, Korman, N, MacCabe, J, Cotes, R.O., Gaughran, F, Taylor, D, Mena, C., Clark, SR, Kwon, JS, Correll, CU, Chan, Sherry, Hahn, M, Kane, John M., Siskind, Dan, McCutcheon, Robert A., Taipale, H, Leung, JG, Eltorki, Y, Takeuchi, H, Fernandez-Egea, E, Gee, S, Jayaram, M, Chan, S., Howes, O, Qubad, M, Hahn, Maggie, Hallak, JEC, Kanazawa, T, O'Donoghue, B, Citrome, L, Pillinger, T., McCutcheon, R.A., Kim, SH, Fleischhacker, W, Myles, N, Lennox, B, Yağcıoğlu, AEA, Oloyede, E, Remington, G, Tandon, R, Roy, M, Smith, L, de Bartolomeis, A, Cotes, Robert O., Lappin, Julia, Korman, N., Kane, JM, Howes, Oliver D., Honer, W, Corbeil, O, Guinart, D, Sommer, I, Bittner, RA, de Filippis, R, Wagner, E, Béchard, L, Hahn, M., Pillinger, Toby, Elkis, H, Lee, J, McCutcheon, RA, Thirthalli, J, Kelly, D., Hasan, A, Northwood, K., Tiihonen, J, Lappin, J., Ayinde, OO, Baptiste, T, Arango, C, de Leon, J, Lappin, J, Šimunović, Filipčić I, Schulte, PFJ, Verdoux, H, ?, ?, Kelly, DL, Freudenreich, O, Crossley, N, Tanzer, T, et al., Luykx, JJ, Mena, Cristián, Bitter, I, Gadelha, A, Mena, C, Every-Palmer, S., Chkonia, E, Lane, H, Nielsen, J, Yung, A, Chen, E, Uchida, H, Myles, Nick, Northwood, Korinne, Sundram, S, Every-Palmer, S, Si, T, Gama, CS, Correll, Christoph, Xin, Y, Korman, Nicole, Chan, S, Cotes, R, Sagud, M, Asmal, L, Siskind, D., Harris, A, Agid, O, Every-Palmer, Susanna, Cordoba, R, Rubio, J, Kelly, Deanna, Ebdrup, BH   +125 more
core   +1 more source