Results 81 to 90 of about 45,210 (266)

Bipolar Disorder and the Risk of Cardiovascular Diseases: A Systematic Review and Meta‐Analysis of Observational Studies

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Bipolar disorder (BD) is a chronic psychiatric illness characterized by recurrent manic and depressive episodes, affecting 2% of the global population. It is associated with premature mortality, including cardiovascular disease (CVD)‐related mortality.
Fernando Daibert de Souza Motta, Matheus de Lima Ruffini, Amanda Cunha Ritter, Sofia Moreira Ferrão, Rodrigo Sousa Silva, Nicole da Silva Mastella, Bruno Braga Montezano, Elias Ajub Neto, Flávio Kapczinski, Jairo Vinícius Pinto, Ives Cavalcante Passos   +10 more
wiley   +1 more source

Audit of the Management of High Clozapine Levels Within Solihull Community Mental Health Teams (CMHTs)

BJPsych Open
Aims To review the practice of management of clozapine plasma levels in Solihull CMHTs between April and September 2023. Birmingham and Solihull Mental Health Foundation Trust (BSMHFT) clozapine guidelines were issued in January 2023 and further ...
Sarah O'Connor, Huma Hashmat
doaj   +1 more source

Clozapine and cardiotoxicity – A guide for psychiatrists written by cardiologists

, 2019
This review discusses the rare but potentially life-threatening cardiovascular side-effects of myocarditis and dilated cardiomyopathy associated with the use of Clozapine. The clinical presentation of these conditions is non-specific, making it difficult
Alice M. Moore, Eromona Whiskey, Rishi K. Patel, Suhki Shergill, Mark Sweeney, Susan Piper, Carla M. Plymen, Graham Cole   +7 more
core   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Isolated nausea and vomiting as the cardinal presenting symptoms of clozapine-induced myocarditis: a case report

BMC Psychiatry, 2020
Background Clozapine is an atypical antipsychotic proven to be superior in the treatment of treatment-resistant schizophrenia. Myocarditis is a rare, but well-known complication of treatment with clozapine.
M. Z. van der Horst, F. van Houwelingen, J. J. Luykx   +2 more
doaj   +1 more source

Clozapine : gestion et défis

, 2023
Reconnaître les différentes indications approuvées et hors-AMM de la clozapine. Évaluer et gérer efficacement les effets indésirables potentiels de la clozapine.
Brian Miller
core   +1 more source

Use of selective serotonin reuptake inhibitors and risk of myeloid malignancy: A nationwide Danish case–control study

British Journal of Haematology, EarlyView.
Summary Preclinical and clinical studies suggest that selective serotonin reuptake inhibitors (SSRIs) can stimulate haematopoiesis by promoting proliferation and mobilization of haematopoietic stem and progenitor cells, but whether SSRI use influences myeloid malignancy risk remains unclear.
Katrine Mose, Anton Pottegård, Mette Reilev, Christen Lykkegaard Andersen, Blánaid Hicks, Mathilde Egelund Christensen   +5 more
wiley   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

There Is Life After the UK Clozapine Central Non-Rechallenge Database

, 2021
Background and Aims: In the United Kingdom, patients on clozapine whose hematological parameters fall below certain thresholds are placed on the Central Non-Rechallenge Database (CNRD), meaning that they cannot be prescribed clozapine again except under ...
MacCabe, James Hunter, Taylor, David, Mijovic, Alek, Shergill, Sukhi S., Helthuis, Marinka, Whiskey, Eromona, Casetta, Cecilia, Dzahini, Olubanke, Segev, Aviv, Gaughran, Fiona, Oloyede, Ebenezer, Sukhi Shergill, Eromona Whiskey, Cecilia Casetta, Alek Mijovic, Fiona Gaughran, David Taylor, Aviv Segev, Ebenezer Oloyede, Marinka Helthuis, James Hunter MacCabe, Olubanke Dzahini   +21 more
core   +1 more source

The Serotonergic and Cholinergic Signaling Pathways Drive Gastric Precancerous Lesions and Its Potential Mechanism

Cancer Science, EarlyView.
Vagal cholinergic neurons promote gastric 5‐HT secretion, which drives gastric precancerous lesions through 5‐HTR1D and TRPV4, highlighting these as candidate targets for early intervention. ABSTRACT Gastric cancer (GC) is a leading lethal malignancy globally. Gastric precancerous lesion (GPL) represents a critical step in GC, but its neural regulatory
Shengli Gao, Xufei Feng, Nana Zhang, Jia Su, Yuyan Wang, Linghan Kong, Jianing Zhou, Hui Dong, Feifei Guo   +8 more
wiley   +1 more source