Results 101 to 110 of about 45,210 (266)
Journal of Oral Rehabilitation, EarlyView.Repeated TMJ injury in mice demonstrated that greater injury severity and female sex exacerbate post‐traumatic TMJ degeneration. While short‐term nociceptor inhibition reduced pain without affecting degeneration, prolonged inhibition modestly attenuated degeneration, suggesting that persistent post‐traumatic pain contributes to TMJ osteoarthritis ...
Ishraq Alshanqiti +4 more
wiley +1 more source
Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont +5 more
wiley +1 more source
, 2020 Background Clozapine is uniquely effective in treatment-resistant psychosis but remains underutilised, partly owing to psychotic symptoms leading to non-adherence to oral medication. An intramuscular formulation is available in the UK but outcomes remain
Whiskey, E., Dzahini, O., Shergill, S.
core
Severe neutropenia unrelated to clozapine in patients receiving clozapine [PDF]
Background: Clozapine is known to cause agranulocytosis. Mandatory monitoring schemes are aimed at reducing the risk of agranulocytosis and of the consequences of agranulocytosis.
Vallianatou, Kalliopi +5 more
core +1 more source
Antipsychotics‐Induced Hyposalivation Mediated by Impaired Salivary Ca2+ Signaling
Oral Diseases, EarlyView.ABSTRACT Objectives Antipsychotic‐induced salivary dysfunction such as hyposalivation is a prevalent clinical challenge that severely compromises oral health and quality of life. Although typical and atypical antipsychotics have their therapeutic target in the central nervous system, their direct molecular mechanisms within the salivary glands remain ...
Chaelin Chung +4 more
wiley +1 more source
Of mice and men—The emerging oral–gut–brain axis of health and disease
Periodontology 2000, EarlyView.Abstract Objectives Oral health's inextricable links to systemic health are highlighted by the emerging oral–gut–brain axis and other well‐known axes. There is growing evidence of a complex oral–gut–brain axis linking mouth and gut microbiomes with the central nervous system.
Yvonne L. Hernandez‐Kapila +1 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil +11 more
wiley +1 more source
Frontiers in PsychiatryBackgroundClozapine has immunomodulatory effects that raised concerns about its potential to exacerbate severe COVID-19. This study examines whether clozapine use is associated with worse COVID-19 outcomes in patients with schizophrenia.MethodsThis ...
Dalia Albahari +6 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato +3 more
wiley +1 more source
European PsychiatryIntroduction Clozapine is a second-generation atypical antipsychotic medication used in patients with treatment-refractory schizophrenia. Its use is limited due to its associated adverse effects, including myocarditis.
U. L. Anyeji, P. Bidkhanian
doaj +1 more source