Results 81 to 90 of about 63,990 (294)

Clozapine prescribing patterns in hospitalised patients in everyday clinical practice

Open Journal of Psychiatry and Allied Sciences, 2020
Aim: Clozapine is the gold standard for treatment-resistant schizophrenia. Despite clear recommendations for use, under-use and excessive delay in the use of clozapine are an ongoing findings in the literature.
Ivana Stašević Karličić, Milena Stašević, Vladan Đorđević, Aleksandra Dutina   +3 more
doaj   +1 more source

Benign ethnic neutropenia: an analysis of prevalence, timing and identification accuracy in two large inner-city NHS hospitals

BMC Psychiatry, 2021
Background Benign ethnic neutropenia (BEN) is the most common cause of chronic neutropenia seen in individuals of African, Middle Eastern and West Indian descent.
Ebenezer Oloyede, Olubanke Dzahini, Nigel Barnes, Aleksandar Mijovic, Shreyans Gandhi, Sara Stuart-Smith, Theo de Witte, David Taylor, Eromona Whiskey   +8 more
doaj   +1 more source

Development and validation of a GC-MS method for the detection and quantification of clotiapine in blood and urine specimens and application to a postmortem case [PDF]

, 2015
INTRODUCTION: Clotiapine is an atypical antipsychotic of the dibenzothiazepine class introduced in a few European countries since 1970, efficient in treatment-resistant schizophrenic patients.
Busardo', FRANCESCO PAOLO, Catanese, Miriam, Mannocchi, Giulio, Pantano, Flaminia, Tittarelli, Roberta, UMANI RONCHI, Federica   +5 more
core   +5 more sources

UHPLC‐QTOFMS Urine Drug Screening With Dilute‐and‐Shoot Sample Preparation and Vacuum‐Insulated Probe‐Heated Electrospray Ionization

Drug Testing and Analysis, EarlyView.
The new ionization technique, vacuum‐insulated probe‐heated electrospray, allows for a simple dilute‐and‐shoot sample preparation to be used with liquid chromatography time‐of‐flight mass spectrometry in urine drug screening. Comparison with a method relying on solid‐phase extraction and conventional electrospray ionization shows improved performance ...
Mira Sundström, Pirkko Kriikku, Ilkka Ojanperä, Carsten Baessmann, Anna Pelander   +4 more
wiley   +1 more source

Clozapine Withdrawal Catatonia: A Case Series and Review of Literature

Annals of Indian Psychiatry
Background: Catatonia has been reported with withdrawal of medications. Among the various psychotropics, clozapine has been implicated to cause catatonia when abruptly withdrawn. The data regarding clozapine withdrawal catatonia are scarce and are mostly
Gopika Jagota, Sandeep Grover
doaj   +1 more source

Flupenthixol in relapse prevention in schizophrenics with comorbid alcoholism: Results from an open clinical study [PDF]

, 2003
Substance use, especially alcoholism, has been recognized as a significant problem in schizophrenic patients, though only a few studies on the effects of pharmacotherapy in these patients have been conducted so far.
Aichmüller, Claus, Bardeleben, Ulrich von, Beneke, Manfred, Glaser, Thomas, Hornung-Knobel, Sybille, Soyka, Michael, Wegner, Ulrike   +6 more
core   +1 more source

Comprehensive Qualitative Drug Screening in Emergency Toxicology Using an Automated LC–MSn System:Simultaneous Quantification of Relevant Drugs and Metabolites in Blood Plasma

Drug Testing and Analysis, EarlyView.
Simultaneous qualitative and quantitative analysis of 62 drugs and seven active metabolites in human blood plasma by automated liquid chromatography linear ion trap mass spectrometry. ABSTRACT Rapid and comprehensive qualitative and quantitative analytical procedures are crucial in 24/7 emergency toxicology (ET) to support diagnosis and treatment of ...
Selina Hemmer, Maximilian Ninnig, Lea Wagmann, Sascha K. Manier, Markus R. Meyer   +4 more
wiley   +1 more source

Effects of haloperidol and atypical neuroleptics on psychomotor performance and driving ability in schizophrenic patients - Results from an experimental study [PDF]

, 2003
The influence of antipsychotic treatment on the neuropsychological and psychomotor performance of schizophrenic patients is still a subject of investigation.
Kagerer, S., Möller, Hans-Jürgen, Soyka, Michael, Winter, C.   +3 more
core   +1 more source

Clozapine is underutilized.

Shanghai archives of psychiatry, 2012
I read the piece by Wang and Li[1] with great interest. The issues surrounding the use of clozapine in China and the United States provide an interesting contrast. Wang and Li suggest that clozapine is over-utilized in China both as a first-line treatment and (in low doses) to augment other antipsychotic agents.
openaire   +3 more sources

Chemogenetic Control of Striatal Astrocytes Improves Parkinsonian Motor Deficits in Mice

Glia, EarlyView.
Dopamine depletion reduces locomotion‐induced calcium activity in dorsal striatal astrocytes. Chemogenetic activation facilitates astrocyte locomotion responses and improves motor behavior in dopamine‐lesioned animals. ABSTRACT Parkinson's disease (PD) is characterized by the degeneration of dopaminergic nigrostriatal inputs, which causes striatal ...
Wesley R. Evans, Sindhuja S. Baskar, Angelica Vellore, Ana Raquel Castro E. Costa, Cynthia Jacob, Sanya Ravoori, Abimbola Arigbe, Rafiq Huda   +7 more
wiley   +1 more source