Results 51 to 60 of about 119,051 (375)
Inhibition of the mTOR Pathway Exerts Cardioprotective Effects Partly through Autophagy in CLP Rats
Background Sepsis-induced myocardial dysfunction is a severe clinical problem. Recent studies have indicated that autophagy and myocardial energy depletion play a major role in myocardial dysfunction during sepsis, a mechanistic target of rapamycin (mTOR)
W. Han+5 more
semanticscholar +1 more source
Conformational control of the bacterial Clp protease by natural product antibiotics.
Covering: up to 2017The bacterial Clp protease is a highly conserved and structurally versatile machine. It has gained a lot of recognition during the last decade as a novel antibacterial drug target with an unprecedented mechanism of action.
Imran T Malik, H. Brötz-Oesterhelt
semanticscholar +1 more source
The clp-paracompact spaces were defined and studied by A. Sondore. These spaces are those such that each clopen cover of them has a locally finite clopen refinement. Then, these spaces are related to ultraparacompact and to clp-compact spaces. In this paper, we obtain a theorem showing that every clp-paracompact Hausdorff space is the image of a clp ...
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An Affinity of Intellectual Liveliness: Uma Conversa com Hans Ulrich Gumbrecht
Entrevista com Hans Ulrich Gumbrecht na Faculdade de Letras da Universidade de Coimbra, conduzida por Fábio Waki e Ana Sabino a 12 de abril de 2019. A conversa lida com vários aspectos do trabalho de Gumbrecht, mas enfatiza a ideia de materialidade e de ...
Waki, Fábio, Sabino, Ana
doaj +1 more source
Orofacial Clefts: Prenatal Diagnosis and Postnatal Management
Orofacial clefts are among the most common congenital malformations which have significant consequences in terms of long term morbidity and health care costs. The overall prevalence of orofacial clefts is estimated to be 9.92 per 10000 births.
Ebru Tarım, Cantekin İskender
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Protective Effects of Human and Mouse Soluble Scavenger-Like CD6 Lymphocyte Receptor in a Lethal Model of Polymicrobial Sepsis [PDF]
Sepsis still constitutes an unmet clinical need, which could benefit from novel adjunctive strategies to conventional antibiotic therapy. The soluble form of the scavenger-like human CD6 lymphocyte receptor (shCD6) binds to key pathogenic components from
Aranda, Fernando+9 more
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Protective effect of Cl-amidine against CLP-induced lethal septic shock in mice
Production of innate and adaptive immune cells from hematopoietic stem cells, and maturation of T lymphocytes are effective immune responses to fight severe microbial infection.
T. Zhao+7 more
semanticscholar +1 more source
Products of sequential CLP-compact spaces are CLP-compact
AbstractIt is shown that the product of finitely many sequential, CLP-compact spaces is CLP-compact.
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TCHR: a framework for tabled CLP [PDF]
AbstractTabled Constraint Logic Programming is a powerful execution mechanism for dealing with Constraint Logic Programming without worrying about fixpoint computation. Various applications, e.g. in the fields of program analysis and model checking, have been proposed.
David S. Warren+2 more
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Towards independent and-parallelism in CLP [PDF]
In this paper we propose a complete scheme for automatic exploitation of independent and-parallelism in CLP programs. We first discuss the new problems involved because of the different properties of the independence notions applicable to CLP. We then show how independence can be derived from a number of standard analysis domains for CLP. Finally,
García de la Banda, M.+2 more
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