Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Using K-Means Cluster Analysis and Decision Trees to Highlight Significant Factors Leading to Homelessness [PDF]
Andrea Yoder Clark +5 more
openalex +1 more source
Pandemic (H1N1) 2009 Cluster Analysis: A Preliminary Assessment [PDF]
Pandemic (H1N1) 2009 virus has been causing major concerns around the world because of its epidemic potential, rapid dissemination, rate of mutations, and the number of fatalities.
Alan Zulich +6 more
core +1 more source
This is a continuation of developing mutation theory in exact WKB analysis using the framework of cluster algebras. Here we study the Schrodinger equation on a compact Riemann surface with turning points of simple-pole type.
Iwaki, Kohei, Nakanishi, Tomoki
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
An Approach for Determining the Number of Clusters in a Model-Based Cluster Analysis
To determine the number of clusters in the clustering analysis that has a broad range of applied sciences, such as physics, chemistry, biology, engineering, economics etc., many methods have been proposed in the literature.
Serkan Akoğul, Murat Erisoglu
semanticscholar +1 more source
National Trends on Agricultural Crops Production: Cluster Analysis [PDF]
Staring from descriptive data on crop production and cultivated area at national level during on fifteen years, the aim of this study is to reveal the trends on crops cultivation.
BOLBOACA, Dr. Sorana D. +2 more
core
Bayes-X: a Bayesian inference tool for the analysis of X-ray observations of galaxy clusters
We present the first public release of our Bayesian inference tool, Bayes-X, for the analysis of X-ray observations of galaxy clusters. We illustrate the use of Bayes-X by analysing a set of four simulated clusters at z=0.2-0.9 as they would be observed ...
Feroz, F. +5 more
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source

