Results 91 to 100 of about 27,265,132 (376)

Cluster randomised trials in the medical literature: two bibliometric surveys [PDF]

, 2004
Background: Several reviews of published cluster randomised trials have reported that about half did not take clustering into account in the analysis, which was thus incorrect and potentially misleading.
A Donner, A Donner, A Donner, C Emslie, CM Wright, CR Elley, D Nutbeam, DG Altman, DG Altman, DM Murray, E Rink, G Meyer, J Cornfield, J Martin Bland, JCFM Wetsteyn, JM Bland, JM Bland, JM Simpson, MAH Russell, MJ Gardner, MJ Gardner, MK Campbell, P Isaakidis, S Puffer, SM Eldridge, SM Kerry, SM Kerry, SM Kerry, SP Varnell   +28 more
core   +4 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Emerging RNA-centric technologies to probe RNA-protein interactions: importance in decoding the life cycle of positive sense single strand RNA viruses and antiviral discovery

Frontiers in Cellular and Infection Microbiology
Positive sense single strand RNA (+ssRNA) viruses are one of the evolutionary successful organisms and many of them pose a significant threat to human health.
Sreemoyee Ghosh, Shivam Kumar, Rohit Verma, Shabnam Ansari, Samrat Chatterjee, Milan Surjit   +5 more
doaj   +1 more source

The X-ray Cluster Dipole [PDF]

, 1997
We estimate the dipole of the whole sky X-ray flux-limited sample of Abell/ACO clusters (XBACs) and compare it to the optical Abell/ACO cluster dipole.
Ebeling H., Harmon R. T., Hudson M. J., Hudson M. J., Kaiser N., Kolokotronis V., Kolokotronis V., Lahav O., Lahav O., Lahav O., Lynden-Bell D., Peacock J. A., Peebles P. J. E., Plionis M., Plionis M., Plionis M., Rowan-Robinson M., Scaramella R., Sutherland W., Tini-Brunozzi P., Trumper J.   +20 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Quantifying Inorganic Nitrogen Assimilation by Synechococcus Using Bulk and Single-Cell Mass Spectrometry: A Comparative Study

Frontiers in Microbiology, 2018
Microorganisms drive most of the major biogeochemical cycles in the ocean, but the rates at which individual species assimilate and transform key elements is generally poorly quantified.
Marco Giardina, Soshan Cheong, Christopher E. Marjo, Peta L. Clode, Peta L. Clode, Peta L. Clode, Paul Guagliardo, Russell Pickford, Mathieu Pernice, Justin R. Seymour, Jean-Baptiste Raina   +10 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

CLUSTER ANALYSIS IN BIOTECHNOLOGY [PDF]

Biotechnologia Acta, 2017
Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology of the National Academy of Sciences of Ukraine, Kyiv The goal of publication was the analysis of cluster methods and possibility of their application in biotechnology.
O. M. Klyuchko
doaj   +1 more source

National Trends on Agricultural Crops Production: Cluster Analysis [PDF]

, 2007
Staring from descriptive data on crop production and cultivated area at national level during on fifteen years, the aim of this study is to reveal the trends on crops cultivation.
BOLBOACA, Dr. Sorana D., JÄNTSCHI, Dr. Lorentz, STOENOIU, Carmen E,   +2 more
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source