Results 51 to 60 of about 161,459 (317)

Metagenomic analysis of dental calculus in ancient Egyptian baboons [PDF]

open access: yes, 2019
Dental calculus, or mineralized plaque, represents a record of ancient biomolecules and food residues. Recently, ancient metagenomics made it possible to unlock the wealth of microbial and dietary information of dental calculus to reconstruct oral ...
Bramanti, Barbara   +7 more
core   +1 more source

Which DNA Damage is Likely to Be Relevant in Hormetic Responses?

open access: yesDose-Response, 2008
Working under the assumption that hormesis is triggered by specific types of DNA damage, this report focuses on the types of damage which form the signature of ionizing radiation.
William A. Bernhard   +2 more
doaj   +1 more source

Orchestrated transcription of biological processes in the marine picoeukaryote Ostreococcus exposed to light/dark cycles [PDF]

open access: yes, 2010
Background: Picoeukaryotes represent an important, yet poorly characterized component of marine phytoplankton. The recent genome availability for two species of Ostreococcus and Micromonas has led to the emergence of picophytoplankton comparative ...
Bouget, François-Yves   +7 more
core   +7 more sources

Microbial differences between dental plaque and historic dental calculus are related to oral biofilm maturation stage [PDF]

open access: yes, 2019
Dental calculus, calcified oral plaque biofilm, contains microbial and host biomolecules that can be used to study historic microbiome communities and host responses.
CJ Adler   +69 more
core   +4 more sources

Methods for Enhancing Clustered Regularly Interspaced Short Palindromic Repeats/Cas9-Mediated Homology-Directed Repair Efficiency

open access: yesFrontiers in Genetics, 2019
The evolution of organisms has provided a variety of mechanisms to maintain the integrity of its genome, but as damage occurs, DNA damage repair pathways are necessary to resolve errors.
Xi-Dian Tang   +5 more
doaj   +1 more source

Glutathione depletion and carbon ion radiation potentiate clustered DNA lesions, cell death and prevent chromosomal changes in cancer cells progeny. [PDF]

open access: yesPLoS ONE, 2012
Poor local control and tumor escape are of major concern in head-and-neck cancers treated by conventional radiotherapy or hadrontherapy. Reduced glutathione (GSH) is suspected of playing an important role in mechanisms leading to radioresistance, and its
Maïté Hanot   +8 more
doaj   +1 more source

Analysis of chromosome positions in the interphase nucleus of Chinese hamster cells by laser-UV-microirradiation experiments [PDF]

open access: yes, 1982
Unsynchronized cells of an essentially diploid strain of female Chinese hamster cells derived from lung tissue (CHL) were laser-UV-microirradiated (=257 nm) in the nucleus either at its central part or at its periphery.
B Dutrillaux   +38 more
core   +1 more source

Beam Energy Considerations for Gold Nano-Particle Enhanced Radiation Treatment [PDF]

open access: yes, 2009
Purpose: A novel approach using nano technology enhanced radiation modalities is investigated. The proposed methodology uses antibodies labeled with organically inert metals with a high atomic number.
Heuvel, F. Van den   +2 more
core   +2 more sources

DNA Damage and Radical Reactions: Mechanistic Aspects, Formation in Cells and Repair Studies

open access: yesCHIMIA, 2008
Several examples of oxidative and reductive reactions of DNA components that lead to single and tandem modifications are discussed in this review.
Jean Cadet   +8 more
doaj   +1 more source

Dissociation Dynamics of XPC-RAD23B from Damaged DNA Is a Determining Factor of NER Efficiency. [PDF]

open access: yesPLoS ONE, 2016
XPC-RAD23B (XPC) plays a critical role in human nucleotide excision repair (hNER) as this complex recognizes DNA adducts to initiate NER. To determine the mutagenic potential of structurally different bulky DNA damages, various studies have been ...
Benjamin Hilton   +6 more
doaj   +1 more source

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