Results 91 to 100 of about 2,744,930 (320)

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Physical Health Portrait and Intervention Strategy of College Students Based on Multivariate Cluster Analysis and Machine Learning

Applied Sciences
With the rapid development of society and technology, the physical health of university students has become a critical concern, influencing both individual well-being and the national talent pool.
Rong Guo, Rou Dong, Ni Lu, Lin Yu, Chaoxian Chen, Yonglin Che, Jiajin Zhang, Jianke Yang   +7 more
doaj   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

A Multidimensional Particle Swarm Optimization-Based Algorithm for Brain MRI Tumor Segmentation

Sensors
Particle Swarm Optimization (PSO) has been extensively applied to optimization tasks in various domains, including image segmentation. In this work, we present a clustering-based segmentation algorithm that employs a multidimensional variant of PSO ...
Zsombor Boga, Csanád Sándor, Péter Kovács   +2 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

A Synergy Between Machine Learning and Formal Concept Analysis for Crowd Detection

IEEE Access
To enhance public safety, crowd detection and prevention systems have essentially become a natural means to manage diverse crowded areas, such as urban settings, transportation hubs, and event venues.
Anas M. Al-Oraiqat, Oleksandr Drieiev, Sattam Almatarneh, Mohammadnoor Injadat, Karim A. Al-Oraiqat, Hanna Drieieva, Yassin M. Y. Hasan   +6 more
doaj   +1 more source

Clustering technique and peer assessment in teaching writing recount text to junior high school students

ELT Forum: Journal of English Language Teaching, 2017
This study was conducted under the consideration of the observation in SMPN 39 Semarang that many students faced problems in learning to write a text.
Eka Yunita Widyawati, Novia Trisanti
doaj   +1 more source

On the Elusiveness of Clusters

IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2012
Rooted phylogenetic networks are often used to represent conflicting phylogenetic signals. Given a set of clusters, a network is said to represent these clusters in the "softwired" sense if, for each cluster in the input set, at least one tree embedded in the network contains that cluster.
Steven Kelk, Leo van Iersel, Celine Scornavacca   +2 more
openaire   +4 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Crime clustering in Yogyakarta: Data analysis 2016-2020 and state responsibility in crime

Jurnal Civics: Media Kajian Kewarganegaraan
Crime often occurs. The crime rate in an area will be different from that of other areas according to the characteristics of the area. The clustering carried out in this study is based on the number of reported crime rates.
Aris Martiana, Nursida Arif, Amika Wardana, Norwaliza Abdul Wahab   +3 more
doaj   +1 more source