Results 61 to 70 of about 589,029 (277)

Cluster algorithm for vertex models [PDF]

open access: yesPhysical Review Letters, 1993
9 pages, Latex, 2 figures in Latex, FSU-SCRI-92 ...
Evertz, H. G., Lana, G., Marcu, M.
openaire   +3 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Subspace clustering of dimensionality-reduced data

open access: yes, 2014
Subspace clustering refers to the problem of clustering unlabeled high-dimensional data points into a union of low-dimensional linear subspaces, assumed unknown.
Bölcskei, Helmut   +2 more
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Clustering graph data: the roadmap to spectral techniques

open access: yesDiscover Artificial Intelligence
Graph data models enable efficient storage, visualization, and analysis of highly interlinked data, by providing the benefits of horizontal scalability and high query performance.
Rahul Mondal   +5 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Comparative Analysis of Predictive Algorithms for Performance Measurement

open access: yesIEEE Access
Predictive algorithms, also known as mathematical models, utilize historical data to accurately predict future outcomes. These algorithms identify patterns and relationships within the data, resulting in precise predictions.
Swati Gupta, Bal Kishan, Preeti Gulia
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

An Overview of Co-Clustering via Matrix Factorization

open access: yesIEEE Access, 2019
Co-clustering algorithms have been widely used for text clustering and gene expression through matrix factorization. In recent years, diverse co-clustering algorithms which group data points and features synchronously have shown their advantages over ...
Renjie Lin, Shiping Wang, Wenzhong Guo
doaj   +1 more source

An analysis framework for clustering algorithm selection with applications to spectroscopy.

open access: yesPLoS ONE, 2022
Cluster analysis is a valuable unsupervised machine learning technique that is applied in a multitude of domains to identify similarities or clusters in unlabelled data. However, its performance is dependent of the characteristics of the data it is being
Simon Crase, Suresh N Thennadil
doaj   +1 more source

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