Results 111 to 120 of about 134,552 (311)

Research of the Start-off Slip Friction Control of Hydraulic Torque Converter Lockup Clutch

open access: yesJixie chuandong, 2016
Taking the Lockup clutch in the hydraulic torque converter as the study object,the strategy of start- off slip friction control for the hydraulic torque converter lockup clutch is studied.
Xue Dianlun, Chang Neng, Guo Xuekai
doaj  

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Egg clutch structure of Rhinella rumbolli (Anura: Bufonidae), a toad from the Yungas of Argentina, with a review of the reproductive diversity in Rhinella [PDF]

open access: yes, 2015
Rhinella rumbolli is a poorly known, medium-sized toad endemic to the Yungas of Argentina. Recent fieldwork allowed observing its peculiar oviposition mode, which is described in this paper.
Baldo, Juan Diego   +3 more
core  

Allometry of reproduction in broad-snouted caiman (Caiman latirostris)

open access: yesBrazilian Journal of Biology, 2001
In the present study regression equations are established between broad-snouted caiman (Caiman latirostris) captive reproductive females snout-vent length (SVL) and body mass (BM) and the following clutch characteristics: egg mass, egg "length" (maximal ...
VERDADE L. M.
doaj  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Telescoping columns [PDF]

open access: yes, 1980
An extendable column is described which consists of several axially elongated rigid structural sections nested within one another. Each section includes a number of rotatably attached screws running along its length.
Mazur, J. T.
core   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

摩擦-牙嵌复合式离合器的研究

open access: yesJixie chuandong, 2011
A friction clutch and jaw combined clutch is proposed and the working principle and action process are analyzed.Control flow of this clutch is proposed,control strategy of this clutch is studied and the whole control system is got,the design basis of the
王春玲, 常山, 闫泽, 宋成军
doaj  

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

open access: yesAging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

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