Results 31 to 40 of about 16,106 (265)
Weak and Tunable Adhesion–Clutch Drives Rapid Cell Migration and Glioblastoma Invasion
Advanced ScienceTo move forward, cells must exert backward forces against their surrounding environment. Recent studies have highlighted the importance of integrin‐independent forces for cell migration; however, the molecular machinery that exerts forces remains unclear.
Kentarou Baba +15 more
doaj +1 more source
The Effects of Viewing Cute Pictures on Performance During a Basketball Free-Throw Task
Frontiers in Psychology, 2021 Previous studies have shown that viewing cute pictures leads to performance improvement in a subsequent fine motor task. We examined the beneficial effects of viewing cute pictures in a more complex sporting skill (i.e., basketball free throws) by ...
Naoki Yoshikawa, Hiroaki Masaki
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
THE EXPERIMENTAL DIDACTIC STAND FOR DETERMINING THE PARAMETERS OF THE GEAR WITH MAGNETORHEOLOGICAL CLUTCH AND BRAKE [PDF]
Scientific Journal of Silesian University of Technology. Series Transport, 2014 In this paper the laboratory stand, designed to be used as a part of the Laboratory of Machine Design and Research which is part of the subject Fundamentals of Machine Design, is presented.
Jerzy BAJKOWSKI
doaj
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Effects of left-hand contraction on tennis serve performance
Frontiers in PsychologyIntroductionThe tennis serve is commonly executed in high-pressure scenarios, often leading to performance decline; a condition commonly referred to as choking under pressure.
Kanta Mizuno, Hiroaki Masaki
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
ELECTROMAGNETIC SYSTEM FOR IMPROVING THE ADHESION OF WHEELS TO RAILS [PDF]
Transport Problems, 2019 The article describes the design of a system used for the improvement of the adhesion of locomotive wheels to rails; the principle of which is based on the electromagnetic feeding of the contact area with the bulk material that has magnetic properties ...
Yuriy OSENIN +4 more
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Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source