Results 41 to 50 of about 40,506 (250)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
THE EXPERIMENTAL DIDACTIC STAND FOR DETERMINING THE PARAMETERS OF THE GEAR WITH MAGNETORHEOLOGICAL CLUTCH AND BRAKE [PDF]
Scientific Journal of Silesian University of Technology. Series Transport, 2014 In this paper the laboratory stand, designed to be used as a part of the Laboratory of Machine Design and Research which is part of the subject Fundamentals of Machine Design, is presented.
Jerzy BAJKOWSKI
doaj
Analyses of Actin Dynamics, Clutch Coupling and Traction Force for Growth Cone Advance
, 2021 To establish functional networks, neurons must migrate to their appropriate destinations and then extend axons toward their target cells. These processes depend on the advances of growth cones that located at the tips of neurites.
Sakumura, Yuichi +11 more
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Effects of left-hand contraction on tennis serve performance
Frontiers in PsychologyIntroductionThe tennis serve is commonly executed in high-pressure scenarios, often leading to performance decline; a condition commonly referred to as choking under pressure.
Kanta Mizuno, Hiroaki Masaki
doaj +1 more source
, 2009 Clutch is the title of the creative portion of my thesis as well as the name of my theory 'clutch' which I outline in the preface section. The purpose of the clutch theory is to recognize modes of inspiration in the body, heart and mind so that the poet ...
Bauge, Jessica M.
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
A fixed energetic ceiling to parental effort in the great tit? [PDF]
, 2000 1. To elucidate the links between avian brood size, parental effort and parental investment, we measured daily energy expenditure (DEEfem), condition (residuals of mass on tarsus) and feeding rate in female great tits Parus major L.
Verhulst, S.; id_orcid +6 more
core +3 more sources