Results 61 to 70 of about 33,738 (312)
Clutching Is Not (Necessarily) the Enemy
Proceedings of the 33rd Annual ACM Conference on Human Factors in Computing Systems, 2015 Clutching is usually assumed to be triggered by a lack of physical space and detrimental to pointing performance. We conduct a controlled experiment using a laptop trackpad where the effect of clutching on pointing performance is dissociated from the effects of control-to-display transfer functions. Participants performed a series of target acquisition
Mathieu Nancel +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
ELECTROMAGNETIC SYSTEM FOR IMPROVING THE ADHESION OF WHEELS TO RAILS [PDF]
Transport Problems, 2019 The article describes the design of a system used for the improvement of the adhesion of locomotive wheels to rails; the principle of which is based on the electromagnetic feeding of the contact area with the bulk material that has magnetic properties ...
Yuriy OSENIN +4 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Torsional vibration analysis of automotive drivelines [PDF]
, 1997 One of the most important source of noise and vibrations associated with vehicles is the vibration of driveline systems. Such phenomena are subjectively associated with customer complaints.
Rabeih, El-Adl Mohammed Aly
core
, 2012 Clutch size is generally considered to be one of the most important determinants of reproductive success and lifetime fitness in birds. It is also perhaps the most well-studied life-history trait in birds, though many reviews have focused on ...
Tony D. Williams
core +1 more source
Biophysical approaches for studying viral entry
FEBS Letters, EarlyView.Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Adhesion-clutch between DCC and netrin-1 mediates netrin-1–induced axonal haptotaxis
Frontiers in Molecular NeuroscienceThe growth cone, a motile structure located at the tip of growing axons, senses extracellular guidance cues and translates them into directional forces that drive axon outgrowth and guidance.
Zhen Qiu +5 more
doaj +1 more source