Results 71 to 80 of about 33,738 (312)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Effect of timing and female quality on clutch size in the Collared Flycatcher Ficedula albicollis
Capsule: Laying date and female age appear to be related to clutch size. Aims: To test two hypotheses ('date' and 'quality'), which might explain why fewer eggs are laid late in the season.
Tóth, László +2 more
core
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The authors propose a method for reducing the loading of mechanical transmission in the shift in the use of microprocessor controller for the compensation of the friction coefficient of the friction clutch during its skid.
V.N. Basalaev
doaj
Development of High Efficiency Dog Clutch with One-Way Mechanism for Stepped Automatic Transmissions
In order to reduce drag losses and a clutch actuator load, the new dog clutch system for stepped automatic transmission is developed. Transmitting torque is converted to the engaging force because rotating shaft and dog clutch are connected with the ...
Isamu Shiotsu +7 more
doaj +1 more source
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
A kis kosársejtek osztályának sajátos altípusa a „clutch” sejt. A „clutch” sejt egy közepes méretű multipoláris idegsejt típus, mely macska és majom elsődleges látókérgének IV. rétegében található meg.
Szűrösová, Tünde
core
Analysis of Hydromechanical Transmission Friction Clutch Failures and Ways to Reduce them
The author determines the main failures of BELAZ hydromechanical transmission; describes the design of hydromechanical transmission friction clutches as well as the types and causes of their failures.
O.A. Shapovalova , A.V. Leshok
doaj
Estimation of Genetic Parameters for Egg Production and Clutch Traits in Lindian Chickens
To accelerate breeding progress for egg production traits in Lindian chickens, the genetic parameters for egg production and clutch-related traits in Lindian chickens were evaluated in the present study.
Jiacheng Liu +9 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source

