Results 81 to 90 of about 135,572 (313)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Hawksbill (Eretmochelys imbricata) and Green Turtle (Chelonia mydas) Nesting and Beach Selection at Príncipe Island, West Africa [PDF]

open access: yes, 2019
Hawksbills (Eretmochelys imbricata) and green turtles (Chelonia mydas) are the predominant nesting sea turtle species on the beaches of Príncipe Island in the Gulf of Guinea.
Bolten, Alan B.   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

MR grease application to a controllable clutch system

open access: yesNihon Kikai Gakkai ronbunshu, 2014
Magneto-Rheological (MR) grease has been applied to a controllable clutch system, and its performance was investigated experimentally. MR fluid is known as a functional fluid whose yield shear stress can be controlled reversibly by the applied magnetic ...
Masato KANEKO, Shin MORISHITA
doaj   +1 more source

Electronic 4-wheel drive control device [PDF]

open access: yes
The internal rotation torque generated during operation of a 4-wheel drive vehicle is reduced using a control device whose clutch is attached to one part of the rear-wheel drive shaft.
Hayato, S.   +3 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Urosaurus graciosus [PDF]

open access: yes, 1988
Number of Pages: 3Integrative BiologyGeological ...
Dickson, Nancy A., Vitt, Laurie J.
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Urbanisation lowers great tit Parus major breeding success at multiple spatial scales [PDF]

open access: yes, 2019
While numerous studies have reported negative effects of urbanisation on birds, few have examined the role of urban scale in influencing breeding success.
Adriaensen, Frank   +5 more
core   +1 more source

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