Results 101 to 110 of about 999 (127)

Increased Levels of Inflammatory Proteins, Including TARC/CCL17, in Skin of AD Patients During JAK Inhibitor Treatment

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 260-263, March 2025.
Celeste M. Boesjes, Lian F. van der Gang, Daphne S. Bakker, C. F. den Hartog Jager, Marlies de Graaf, Marjolein S. de Bruin‐Weller, Femke van Wijk, Edward F. Knol   +7 more
wiley   +1 more source

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, Volume 158, Issue 6, Page 1617-1627, 15 March 2026.
What's new? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source

Verekitug, a Novel Antibody Antagonist to the TSLP Receptor in Adults with Asthma: A 32‐Week Randomized Phase 1b Multiple Ascending‐Dose Trial

Clinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 782-790, March 2026.
Verekitug, a novel, high‐affinity, fully human monoclonal antibody targeting thymic stromal lymphopoietin receptor (TSLPR), is in development as a potential treatment for severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), and chronic obstructive pulmonary disease (COPD).
Dave Singh, Chaim M. Brickman, Peter Lloyd, Ashish Kalra, Subhabrata Biswas, Arkadeep Sinha, Alex Mulvanny, Sumathi Sivapalasingam, Oren M. Becker, Aaron Deykin   +9 more
wiley   +1 more source

Compartment‐guided assembly of large‐scale molecular models with Bentopy

Protein Science, Volume 35, Issue 3, March 2026.
Abstract Molecular dynamics simulations of whole cells and organelles aim to transform cell biology by providing a molecular view into the crowded cellular environment. However, constructing suitable starting configurations remains a major bottleneck due to their size and complexity.
M. S. S. Westendorp, J. A. Stevens, C. M. Brown, A. C. Dommer, T. A. Wassenaar, B. M. H. Bruininks, S. J. Marrink   +6 more
wiley   +1 more source

Profiling and Characterization of Seed Storage Proteins From Borage (Borago officinalis L.) Pressed Cake as a Novel Plant‐Based Protein Source

Sustainable Food Proteins, Volume 4, Issue 1, March 2026.
Borage (Borago officinalis L.) pressed cake, a by‐product of oil extraction, was profiled and characterized to evaluate its potential as a sustainable, plant‐based protein source. Protein fractionation revealed glutelin‐like proteins as predominant, accompanied by 2S albumin, 7S, and 11S globulin‐type proteins. Proteins exhibited high thermal stability
Suneru P. Perera, Rhea Thommana, Dierdre Culbert, Janiko Lindain, Thushan S. Withana‐Gamage   +4 more
wiley   +1 more source

Blockchain and Digital Technologies in the Telecommunications Industry

Thunderbird International Business Review, Volume 68, Issue 2, Page 139-163, March/April 2026.
ABSTRACT This article examines how fourth industrial revolution (4IR) technologies, specifically blockchain and digital twin technologies, can be utilized to address the energy supply challenge and enhance the management of distributed telecom infrastructure assets in a research context.
Charles Okeyia, Nuno Marques de Almeida, Joe Amad‐Echendu, Simplice A. Asongu   +3 more
wiley   +1 more source

Supplementation of Hermetia Illucens Larvae to Improve Growth Performance, Meat Quality, and Intestinal Microbiology of Broiler in a Cost‐Effective Manner

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Hermetia illucens larvae meal (HIL) improved broiler growth, carcass yield, gut microbiology, and profitability, with the highest performance observed at 12% inclusion. However, lower inclusion levels (4%) offered a better balance by enhancing meat quality and maintaining favourable fatty acid profiles while still supporting productive and economic ...
Sonia Tabasum Ahmed, Md. Masudul Hassan, Mst. Mayeeda Parvin, Tayeaba Jannat, Mohammad Rashedol Alam Palash   +4 more
wiley   +1 more source

Does Working From Home Kill Innovation? Examining the Relationship Between Working From Home and Innovative Work Behaviour

Creativity and Innovation Management, Volume 35, Issue 1, Page 3-16, March 2026.
ABSTRACT A large proportion of employees regularly work from home despite doubts about their ability to be innovative while working remotely. The relationship between working from home and innovative work behaviour is a pressing issue that has produced ambivalent research results, presumably because the mechanisms that underpin the relationship are ...
Jörn Brandt, René Schmoll
wiley   +1 more source

Championing Better Ideas: Workplace Dignity as an Amplifier of Innovative Work Behaviour

Creativity and Innovation Management, Volume 35, Issue 1, Page 210-230, March 2026.
ABSTRACT Innovation is a cornerstone of organisational success and, in some cases, survival. As innovation is a decidedly human activity, understanding social contexts and socio‐psychological conditions that may motivate or hinder employees' innovation efforts is critical.
Timo Müller, Thomas K. Maran, Sebastian Gauster, Kurt Matzler, Kristen Lucas   +4 more
wiley   +1 more source

Genetic Parameter Estimation for Pregnancy Loss and Their Association With Reproductive and Growth Traits in Brahman Cattle Under Extensive Tropical Conditions

Journal of Animal Breeding and Genetics, Volume 143, Issue 2, Page 365-374, March 2026.
ABSTRACT This study estimated genetic parameters for pregnancy loss (PL) in Brahman cattle and evaluated the genetic correlation of PL with growth and reproductive traits using both the pedigree relationship matrix (A) and pedigree plus genomic relationship matrix (H). Data were collected from two herds in Bolivia, focusing on three age groups: heifers,
Daniel Cardona‐Cifuentes, Lucia G. de Albuquerque, Milagros Arias, Sindy Caivio‐Nasner, Luis Camaripano, Luis G. Gonzalez‐Herrera, Patricia I. Schmidt, Fernando Baldi   +7 more
wiley   +1 more source