Results 141 to 150 of about 7,662,716 (290)

Physico-chemical interaction between sodium alginate (ALG-Na), polyvinylpyrrolidone (PVP), sodium carboxymethylcellulose (CMC-Na) and solvent.

open access: yesActa poloniae pharmaceutica, 1995
Physico-chemical interactions between sodium alginate (ALG-Na), polyvinylpyrrolidone (PVP), sodium carboxymethylcellulose (CMC-Na) and solvent were examined. The performed studies involve effect of concentration of macromolecule compounds, electrolytes and pH value of the system.
M, Górecki, J, Bugaj
openaire   +1 more source

POTENSI SUMBER DAYA ALAM INDONESIA SEBAGAI BAHAN BAKU ALTERNATIF PEMBUATAN CARBOXYMETHYLCELLULOSE – Natrium (CMC-Na) : review

open access: yesMajalah Farmaseutik
Carboxymethylcellulose – Natrium (CMC-Na) merupakan salah satu senyawa turunan dari selulosa yang memiliki berbagai kegunaan baik pada bidang farmasi, tekstile, konstruksi dan makanan. CMC-Na dapat diperoleh dari bahan alam yang mengandung selulosa seperti batang tumbuhan, kayu, daun, kulit buah, tangkai maupun serabut.
Nugraheni, Heka Mareta   +2 more
openaire   +2 more sources

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

open access: yesAdvanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi   +11 more
wiley   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

open access: yesAdvanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang   +10 more
wiley   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

open access: yesAdvanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou   +8 more
wiley   +1 more source

Pengaruh CMC-Na Terhadap Formulasi Gel Hand Sanitizer Ekstrak Etanol Bunga Rosella (Hibiscus sabdariffa Linn)

open access: yesJurnal Farmasi Tinctura
Sediaan gel hand sanitizer mempunyai kelebihan yaitu dapat digunakan secara cepat tanpa memerlukan air, dan manfaat bunga rosella adalah dapat berfungsi sebagai antibakteri. CMC Na berfungsi sebagai bahan pembentuk gel karena turunan selulosa mudah mengembang jika ditambhakna dengan air panas dan akan membentuk cairan kental jernih yang bersifat netral.
Sony Andika Saputra   +2 more
openaire   +1 more source

Transposable Element Dynamics Drive the Genomic Evolution and Phenotypic Diversification of Allotetraploid Common Carp

open access: yesAdvanced Science, EarlyView.
By integrating 516 whole‐genome resequencing datasets and 236 transcriptomes of allotetraploid common carp, this study establishes the first population‐scale atlas of transposable element (TE) variation in teleost species. TE bursts, relaxed purifying selection, and lineage‐specific loss of ancient insertions shape genome evolution and phenotypic ...
Shuimu Hu   +11 more
wiley   +1 more source

RBM25 Drives Hepatocellular Carcinoma Progression by Stabilizing YAP Through Regulating Oncogenic Splicing‐switch of MYPT1

open access: yesAdvanced Science, EarlyView.
This study establishes that the RBM25‐PRPF40A interaction modulates MYPT1 splicing, promoting the production of the oncogenic long isoform. This isoform stabilizes YAP by suppressing its phosphorylation and subsequent proteasomal degradation, ultimately accelerating tumor growth.
Wenjing Zhang   +14 more
wiley   +1 more source

Modulation of the TGF‐β/Smad Signaling Pathway by a Bioactive Oxidized Polygonati Rhizoma Polysaccharide Crosslinked Chitosan Hydrogel as Therapeutic Carrier for Parkinson's Disease Treatment

open access: yesAdvanced Science, EarlyView.
An injectable, self‐healing COPRP hydrogel integrates structurally defined oxidized Polygonati rhizoma polysaccharide with carboxymethyl chitosan through dynamic Schiff‐base crosslinking. The bioactive matrix scavenges reactive oxygen species, suppresses neuroinflammation, protects dopaminergic neurons, and supports sustained levodopa release.
Peng Dai   +10 more
wiley   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

open access: yesAdvanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He   +7 more
wiley   +1 more source

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