Results 121 to 130 of about 195,243 (312)

Author Correction: Reply to: Concerns about global phosphorus demand for lithium-iron-phosphate batteries in the light electric vehicle sector

Communications Materials, 2022
Chengjian Xu, Qiang Dai, Linda Gaines, Mingming Hu, Arnold Tukker, Bernhard Steubing   +5 more
doaj   +1 more source

Cases of Patients Treated in Countries With Limited Resources and Discussed by Experts of the International CML Foundation (iCMLf)—Case No. 1: A Boy Presenting With Priapism and Loss of Vision

Case Reports in Oncological Medicine
Pediatric chronic myeloid leukemia (pCML) is a rare malignancy accounting for only 2%–3% of all childhood leukemias. Due to this rarity, familiarity with pCML is limited among most pediatric practitioners, including even pediatric hemato-oncologists.
Nirmalya Roy Moulik, Arlene Harriss-Buchan, Guiseppe Saglio, Nicola Evans, Meinolf Suttorp   +4 more
doaj   +1 more source

STEP analysis of macro-environmental factors affecting medical and drug care for patients with chronic myeloid leukemia

Фармакоэкономика
Objective: to conduct a STEP analysis (social, technological, economic, political) of macro-environmental factors influencing medical and drug care for patients with chronic myeloid leukemia (CML).Material and methods. The materials used were information
A. V. Zhuravlev, O. I. Knysh
doaj   +1 more source

Energy and Environmental Performance of Bioethanol from Different Lignocelluloses

International Journal of Chemical Engineering, 2010
Climate change and the wish to reduce the dependence on oil are the incentives for the development of alternative energy sources. The use of lignocellulosic biomass together with cellulosic processing technology provides opportunities to produce fuel ...
Lin Luo, Ester van der Voet, Gjalt Huppes   +2 more
doaj   +1 more source

Calcium signaling in plant defense

New Plant Protection, EarlyView.
Calcium signaling acts as a central hub in plant immunity, translating pathogen perception into defense responses. This review highlights the channels, sensors, and signaling networks involved, and discusses how pathogens subvert calcium dynamics, as well as how this knowledge may inspire innovative strategies for engineering durable crop resistance ...
Lifan Sun, Yu Wang, Jie Zhang
wiley   +1 more source

Imatinib-resistance without BCR/ABL Point Mutation in Chronic Myeloid Leukemia

Caucasian Medical Journal
Chronic myeloid leukemia (CML) is a myeloproliferative bone marrow neoplasm that occurs because of a fusion gene called BCR-ABL1. Imatinib -the inhibitor of this fusion geneis the target therapy in CML.
Aytan Shirinova
doaj   +1 more source

Disarming the Hsp70–Bim Alliance: Small‐Molecule and Peptidic Disruptors of a Chaperone‐Apoptotic Switch in Cancer

ChemistryOpen, EarlyView.
Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel, Mohammed Al‐zharani, Lina M. Alneghery, Noha A. Ahmed, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi   +5 more
wiley   +1 more source

Management of children and adolescents with chronic myeloid leukemia in blast phase: International pediatric CML expert panel recommendations [PDF]

, 2023
Stephanie Sembill, Maria Ampatzidou, Sonali Chaudhury, Michael Dworzak, Krzysztof Kałwak, Axel Karow, Alexander Kiani, Manuela Krumbholz, Maaike Luesink, Nora Naumann‐Bartsch, Barbara De Moerloose, Michael Osborn, Kirk R. Schultz, Petr Sedláček, Fiorina Giona, C. Michel Zwaan, Hiroyuki Shimada, Birgitta Versluijs, Frédéric Millot, Nobuko Hijiya, Meinolf Suttorp, Markus Metzler   +21 more
openalex   +1 more source

Engineering Dosimetric Excellence In Total Body Irradiation: Tomotherapy‐Driven Protocols for Precision and Reproducibility

Precision Radiation Oncology, EarlyView.
• Objective: Assess helical Tomotherapy‐based TBI for clinical feasibility, dosimetric reproducibility, and in‐vivo accuracy using dual‐orientation simulation and patient‐specific QA. • Methodology: Implementation of ArcCHECK 3D diode array, ionization chamber verification, and in‐vivo dosimetry with OSLDs at 16 anatomical sites to ensure precise dose ...
Sandeep Singh, Dipesh, Supratik Sen, Abhay Kumar Singh, Mahipal, Manindra Bhushan, Jaskaran Singh Sethi, David K. Simson, Munish Gairola   +8 more
wiley   +1 more source

Disease–Drug–Drug Interaction of Imatinib in COVID‐19 ARDS: A Pooled Population Pharmacokinetic Analysis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.
ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said, Job R. Schippers, Leila Atmowihardjo, Yingxue Li, Mick S. van der Plas, Harm J. Bogaard, Lieuwe D. J. Bos, Ron A. A. Mathôt, Jurjan Aman, Eleonora L. Swart, Imke H. Bartelink   +10 more
wiley   +1 more source