Results 91 to 100 of about 570,811 (281)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
CONSIDERACIONES TRIBUTARIAS GENERALES SOBRE EL BITCOIN [PDF]
Crónica Tributaria, 2019 El crecimiento exponencial de los bitcoins ha llevado a la necesidad de la AEAT de potenciar sus herramientas de seguimiento de las transacciones relacionadas con monedas virtuales, y a la Dirección General de Tributos a pronunciarse (aunque de manera ...
Diego de Miguel Hernando +2 more
doaj
Труды по прикладной ботанике, генетике и селекции, 2019 Background. In breeding work, it is necessary to take into account such an important feature as male sterility of the hybrids obtained. If a plant has visually visible anthers and pollen, the quality of the pollen grains themselves may be low.
O. N. Voronova, V. A. Gavrilova
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Труды по прикладной ботанике, генетике и селекции, 2018 As CMS sources 3 flax lines were used: gc-204 (open flower, sterile anthers), gc-208 and gc-188 are self fertile, their sterility occurs only in hybridization with other lines.
E. A. Porokhovinova
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CMS Data Analysis: Current Status and Future Strategy
, 2003 We present the current status of CMS data analysis architecture and describe work on future Grid-based distributed analysis prototypes. CMS has two main software frameworks related to data analysis: COBRA, the main framework, and IGUANA, the interactive ...
Innocente, Vincenzo
core +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Engineering Analysis of CMS Casing
Механика машин, механизмов и материалов, 2014 In the article the methodological requirements that are indispensable for the implementation of construction documents for the production and operation of developed structures and facilities in order to support the transition of products into commodities
L.V. Larchenkov +2 more
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, 2008 Product sheet describing ULCC's Hosted Content Management Systems ...
Bush, Tim, Steiner, Frank
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