Results 61 to 70 of about 572,784 (238)

Implementasi E-Learning Menggunakan CMS Moodle Untuk Meningkatkan Aktivitas Belajar Siswa

open access: yesJurnal Komputer Terapan, 2016
Kemajuan Teknologi Informasi dan Komunikasi (TIK) dalam dunia pendidikan membuka peluang bagi pendidik untuk mewujudkan pembelajaran yang berpusat kepada siswa.
Iga Setia Utami
doaj  

A clinical comparison of high dose and low dose of Suxamethonium

open access: yesJournal of College of Medical Sciences-Nepal, 2014
Background: Suxamethonium having its rapid onset and short duration of action makes this drug unique amongst the neuromuscular blocking drugs described so far.
RK Yadav, PC Majhi, D Tiwari
doaj   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

DEVELOPMENT OF A WEBSITE TO PROVIDE COPYRIGHTING SERVICES

open access: yesРадіоелектронні і комп'ютерні системи, 2018
The article deals with the task of developing information technology for the provision of copywriting services. The topic of the article is due to the fact that any Internet resource requires the availability of relevant content for further development ...
Святослав Геннадійович Ігунов   +2 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

KARAKTERISTIK MIKROKAPSUL ANTOSIANIN UBI JALAR UNGU DENGAN TEKNIK SPRAY DRYING

open access: yesJurnal Teknologi Industri Pertanian, 2019
Anthocyanin is a source of natural dyes that can replace synthetic dyes. Its nature which is susceptible to certain environmental conditions limits its usefulness in food processing, so it is necessary to encapsulate it in a matrix in the form of ...
Anting Wulandari   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Los procesos de titulización de activos: Comentarios al precedente de observancia obligatoria emitido por la superintendencia del mercado de valores

open access: yesThēmis, 2022
Recientemente, en el Perú, la SMV ha emitido un Precedente de Observancia Obligatoria en el que se ha puesto en cuestionamiento algunos aspectos referentes a dos fideicomisos de titulización.
Miguel Antonio Viale Leo   +1 more
doaj  

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