Results 81 to 90 of about 572,784 (238)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Sistemas Gestores de Contenido (CMS). La solución ideal en la Web

open access: yesIngenius: Revista de Ciencia y Tecnología, 2008
Sistemas Gestores de Contenido (CMS).
Rodolfo Bojorque
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Compressible Navier-Stokes Equations in Cylindrical Passages and General Dynamics of Surfaces—(I)-Flow Structures and (II)-Analyzing Biomembranes under Static and Dynamic Conditions

open access: yesMathematics, 2019
A new approach to solve the compressible Navier-Stokes equations in cylindrical co-ordinates using Geometric Algebra is proposed. This work was recently initiated by corresponding author of this current work, and in contrast due to a now complete ...
Terry E. Moschandreou, Keith C. Afas
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

CONSIDERACIONES TRIBUTARIAS GENERALES SOBRE EL BITCOIN [PDF]

open access: yesCrónica Tributaria, 2019
El crecimiento exponencial de los bitcoins ha llevado a la necesidad de la AEAT de potenciar sus herramientas de seguimiento de las transacciones relacionadas con monedas virtuales, y a la Dirección General de Tributos a pronunciarse (aunque de manera ...
Diego de Miguel Hernando   +2 more
doaj  

Quantitative and qualitative analysis of sunflower pollen (Helianthus L.) and it’s use in breeding work

open access: yesТруды по прикладной ботанике, генетике и селекции, 2019
Background. In breeding work, it is necessary to take into account such an important feature as male sterility of the hybrids obtained. If a plant has visually visible anthers and pollen, the quality of the pollen grains themselves may be low.
O. N. Voronova, V. A. Gavrilova
doaj   +1 more source

RPC Gap Production and Performance for CMS RE4 Upgrade

open access: yes, 2014
CMS experiment constructed the fourth Resistive Plate Chamber (RPC) trigger station composed of 144 RPCs to enhance the high momentum muon trigger efficiency at both endcap regions. All new CMS endcap RPC gaps are produced in accordance with QA and QC at
Kang, Min Ho   +2 more
core   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

Engineering Analysis of CMS Casing

open access: yesМеханика машин, механизмов и материалов, 2014
In the article the methodological requirements that are indispensable for the implementation of construction documents for the production and operation of developed structures and facilities in order to support the transition of products into commodities
L.V. Larchenkov   +2 more
doaj  

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