Results 171 to 180 of about 234,696 (305)

CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire.

Blood, 2015
Yvonne Suessmuth, Rithun Mukherjee, Benjamin K. Watkins, Divya Koura, Knut Finstermeier, C. Desmarais, L. Stempora, J. Horan, A. Langston, M. Qayed, H. Khoury, A. Grizzle, Jennifer A. Cheeseman, Jason A. Conger, J. Robertson, Aneesah P. Garrett, A. Kirk, E. Waller, B. Blazar, A. Mehta, H. Robins, L. Kean   +21 more
semanticscholar   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Beyond CD4: Posterior segment findings and virologic-immunologic predictors in highly active antiretroviral therapy-naïve HIV patients. [PDF]

Indian J Ophthalmol
Hayat SC, Yilmaz YC, Gunduz A, Uran M, Ozal SA.   +4 more
europepmc   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Case report: Maribavir as salvage therapy for multidrug-resistant CMV DNAemia in a non-transplant patient with ocular cicatricial pemphigoid. [PDF]

IDCases
Vaidyanathan BR, Balaji A.
europepmc   +1 more source

The skeleton of the green Iguana iguana (Squamata: Iguanidae) and its intraspecific morphological variation

The Anatomical Record, EarlyView.
Abstract The green iguana (Iguana iguana) is an iguanine lizard with herbivorous and arboreal habits, whose distribution spans through South America, Central America to the south of North America. Although the genus Iguana is well‐known, the species still lacks a comprehensive and up‐to‐date anatomical study, particularly addressing the axial skeleton,
Vieno Rosa, Marcos Vinícius Coelho, Camila Cupello   +2 more
wiley   +1 more source

Cytomegalovirus and Aging-How Can the Field Move Forward? [PDF]

J Infect Dis
Boeckh M, Corey L.
europepmc   +1 more source

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, EarlyView.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source

CMV-specific T cells generated from naïve T cells recognize atypical epitopes and may be protective in vivo

Science Translational Medicine, 2015
P. Hanley, J. Melenhorst, S. Nikiforow, P. Scheinberg, J. Blaney, Gail J. Demmler-Harrison, C. Cruz, S. Lam, R. Krance, Kathryn S. Leung, C. Martinez, Hao Liu, D. Douek, Helen E. Heslop, C. Rooney, E. Shpall, A. Barrett, John R. Rodgers, Catherine M. Bollard   +18 more
semanticscholar   +1 more source