Results 51 to 60 of about 301,575 (326)

Engineering extracellular vesicles as novel treatment options: exploiting herpesviral immunity in CLL

open access: yesJournal of Extracellular Vesicles, 2019
Extracellular vesicles (EVs) are important mediators of cell–cell communication. Intriguingly, EVs can be engineered and thus exploited for the targeted transfer of functional proteins of interest. Thus, engineered EVs may constitute attractive tools for
Kathrin Gärtner   +3 more
doaj   +1 more source

Myocardial Ischemia and Reperfusion Leads to Transient CD8 Immune Deficiency and Accelerated Immunosenescence in CMV-Seropositive Patients [PDF]

open access: yes, 2014
Rationale: There is mounting evidence of a higher incidence of coronary heart disease (CHD) in cytomegalovirus (CMV) seropositive individuals. Objective: The aim of this study was to investigate whether acute MI triggers an inflammatory T-cell ...
Bagnall, Alan   +14 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Multisystem cytomegalovirus end-organ disease in a patient with advanced HIV

open access: yesSouthern African Journal of Infectious Diseases, 2022
Cytomegalovirus (CMV) infection is common in people living with HIV, but multisystem CMV end-organ disease (EOD) is rare following the introduction of effective antiretroviral therapy.
Ruan Spies   +4 more
doaj   +1 more source

Minimal Rank Decoupling of Full-Lattice CMV Operators with Scalar- and Matrix-Valued Verblunsky Coefficients [PDF]

open access: yes, 2008
Relations between half- and full-lattice CMV operators with scalar- and matrix-valued Verblunsky coefficients are investigated. In particular, the decoupling of full-lattice CMV operators into a direct sum of two half-lattice CMV operators by a ...
Clark, Stephen   +2 more
core   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

The Prevalence of Herpes Virus Infections in the Active Phase in Hospitalized Children with Rotavirus Infection

open access: yesДетские инфекции (Москва), 2018
Under the supervision there were 301 children hospitalized in an infectious hospital with a diagnosis of rotavirus infection. All children were examined for the presence of human herpes virus DNA 4, 5 and type 6 (EBV, CMV, HHV6) in the blood.
V. V. Krasnov   +3 more
doaj   +1 more source

Association of Cytomegalovirus DNA and Immunologic Markers of Cardiovascular Disease. [PDF]

open access: yes, 2019
BackgroundPersons living with human immunodeficiency virus (HIV) (PLWH) with high cytomegalovirus (CMV)-specific interferon (IFN) γ response have increased numbers of endothelium homing receptor (CX3CR1)+-expressing cells that are associated with ...
Garg, Ankita   +4 more
core  

Reflectionless CMV matrices and scattering theory

open access: yes, 2014
Reflectionless CMV matrices are studied using scattering theory. By changing a single Verblunsky coefficient a full-line CMV matrix can be decoupled and written as the sum of two half-line operators. Explicit formulas for the scattering matrix associated
Chu, Sherry   +2 more
core   +1 more source

In vivo application of recombinant interleukin 2 in the immunotherapy of established cytomegalovirus infection [PDF]

open access: yes, 1987
We have shown in a murine model system for cytomegalovirus (CMV) disease in the immunocompromised host that in vivo application of recombinant human IL-2 (rhIL-2) can enhance the antiviral effect of a limited number of CD8+T lymphocytes, not only in ...
Koszinowski, Ulrich H.   +2 more
core   +3 more sources

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