Results 71 to 80 of about 234,696 (305)

Ongoing burden of disease and mortality from HIV/CMV coinfection in Africa in the antiretroviral therapy era

open access: yesFrontiers in Microbiology, 2015
Human Cytomegalovirus (CMV) is a well-recognized pathogen in the context of HIV infection, but since the roll out of ART, clinical and scientific interest in the problem of HIV/CMV coinfection has diminished.
E. Adland   +3 more
semanticscholar   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino   +12 more
wiley   +1 more source

THE SOCIO-MEDICAL CHARACTERISTICS OF WOMEN WITH THREATENED PRETERM LABOR

open access: yesАкушерство, гинекология и репродукция, 2016
Objective: to investigate health and social factors leading to the emergence of threatening preterm birth.Material and methods: This study was designed to evaluate the significance of social conditions, professional and material factors, obstetric and ...
A. I. Malyshkina   +4 more
doaj   +1 more source

Conductive Hydrogels for Exogenous Sensing and Cell Fate Control

open access: yesAdvanced Materials, EarlyView.
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar   +15 more
wiley   +1 more source

Cytomegalovirus (CMV) seropositivity decreases B cell responses to the influenza vaccine

open access: yesVaccine, 2015
Cytomegalovirus (CMV)-seropositivity has been shown to have a negative effect on influenza vaccine-specific antibody responses. In this paper we confirm and extend these results showing for the first time a negative association between CMV-seropositivity
D. Frasca   +4 more
semanticscholar   +1 more source

Circulating Cytomegalovirus (CMV)‐Infected Endothelial Cells in Marrow Transplant Patients with CMV Disease and CMV Infection [PDF]

open access: yesThe Journal of Infectious Diseases, 1997
Circulating cytomegalovirus (CMV)-infected endothelial cells (CCIC) have been found in immunocompromised patients with CMV disease and have been associated with disease severity. The frequency of CCIC in marrow transplant recipients was studied to determine its use for distinguishing between CMV pneumonia and asymptomatic CMV infection. CCIC were found
B, Salzberger, D, Myerson, M, Boeckh
openaire   +2 more sources

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

open access: yesAdvanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu   +12 more
wiley   +1 more source

Cytomegalovirus Duodenitis in a Renal Transplant Patient Presenting with Signs of Gastrointestinal Bleeding: A Case Report

open access: yesHaseki Tıp Bülteni, 2020
Cytomegalovirus (CMV) is a common virus that causes opportunistic infections in many organ systems in immunocompromised patients. CMV infections are also an important problem in renal transplant patients.
Atilla Bulur   +3 more
doaj   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia   +17 more
wiley   +1 more source

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

open access: yesAdvanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy