Results 91 to 100 of about 234,696 (305)
UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source
There are many problems during cultivation of ornamental plants arising from diseases and pests. Viral borne pathogens, among these diseases, have a distinctive importance compared to other plant diseases due to their easy mechanical transmission from ...
Ali Karanfi̇l +2 more
doaj +2 more sources
Cytomegalovirus oesophagitis in an HIV-infected patient
Gastrointestinal (GI) involvement of cytomegalovirus (CMV) infection is being recognized with increased frequency in patients with acquired immunodeficiency syndrome (AIDS).
Naveen Kishoria +5 more
doaj
New advances in CMV and immunosenescence.
Immunosenescence, defined as the age-associated dysregulation and dysfunction of the immune system, is characterized by impaired protective immunity and decreased efficacy of vaccines.
P. Sansoni +39 more
semanticscholar +1 more source
We studied cytomegalovirus (CMV) pp65 positive cells (pp65+ cells) in 275 peripheral blood (PB) samples obtained from 157 patients with clinical symptoms such as fever and diarrhea and in 8 biopsy specimens diagnosed as CMV disease immunohistochemically and immunocytologically using the anti-CMV pp65 antibody.
openaire +3 more sources
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang +8 more
wiley +1 more source
Majid Moshirfar,1– 3 Dallin C Milner,4 Preston A Baker,5 Shannon E McCabe,1 Yasmyne C Ronquillo,1 Phillip C Hoopes1 1Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA; 2John A.
Moshirfar M +5 more
doaj
IMMUNOMODULATORS IN OPPORTUNISTIC INFECTIONS TREATMENT
. The immune status and the level of specific antibodies to Cytomegalovirus (121 patients) or Mycoplasma pneumoniae (129 patients) were tested in 250 patients aged 19–56 years old. This cohort was divided for three groups. Seventy eight patients with low
A. P. Toptygina +2 more
doaj +1 more source
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang +15 more
wiley +1 more source
Purpose: To evaluate the TORCH profile (Toxoplasma gondii, rubella, cytomegalovirus, and herpes simplex virus1 and 2) of all patients with congenital cataract excluding traumatic cataracts aged 0-4 yrs over a period 12 months at a tertiary eye hospital ...
K Tejaswi +3 more
doaj +1 more source

