Results 91 to 100 of about 234,696 (305)

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

open access: yesAdvanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro   +7 more
wiley   +1 more source

INVESTIGATION OF CUCUMBER MOSAIC VIRUS INFECTION BY SEROLOGICAL AND MOLECULAR METHODS ON ORNAMENTAL BULBOUS PLANTS IN ÇANAKKALE PROVINCE AND ITS DISTRICTS

open access: yesTrakya University Journal of Natural Sciences, 2016
There are many problems during cultivation of ornamental plants arising from diseases and pests. Viral borne pathogens, among these diseases, have a distinctive importance compared to other plant diseases due to their easy mechanical transmission from ...
Ali Karanfi̇l   +2 more
doaj   +2 more sources

Cytomegalovirus oesophagitis in an HIV-infected patient

open access: yesCurrent Medicine Research and Practice, 2013
Gastrointestinal (GI) involvement of cytomegalovirus (CMV) infection is being recognized with increased frequency in patients with acquired immunodeficiency syndrome (AIDS).
Naveen Kishoria   +5 more
doaj  

New advances in CMV and immunosenescence.

open access: yesExperimental Gerontology, 2014
Immunosenescence, defined as the age-associated dysregulation and dysfunction of the immune system, is characterized by impaired protective immunity and decreased efficacy of vaccines.
P. Sansoni   +39 more
semanticscholar   +1 more source

Utility of Anti-cytomegalovirus (CMV) pp65 Antibody and Cytology in CMV Antigenemia and CMV Disease Diagnosis

open access: yesJournal of the Japanese Association for Infectious Diseases, 2006
We studied cytomegalovirus (CMV) pp65 positive cells (pp65+ cells) in 275 peripheral blood (PB) samples obtained from 157 patients with clinical symptoms such as fever and diarrhea and in 8 biopsy specimens diagnosed as CMV disease immunohistochemically and immunocytologically using the anti-CMV pp65 antibody.
openaire   +3 more sources

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang   +8 more
wiley   +1 more source

Corneal Refractive Surgery in Patients with a History of Herpes Simplex Keratitis: A Narrative Review

open access: yesClinical Ophthalmology, 2020
Majid Moshirfar,1– 3 Dallin C Milner,4 Preston A Baker,5 Shannon E McCabe,1 Yasmyne C Ronquillo,1 Phillip C Hoopes1 1Hoopes Vision Research Center, Hoopes Vision, Draper, UT, USA; 2John A.
Moshirfar M   +5 more
doaj  

IMMUNOMODULATORS IN OPPORTUNISTIC INFECTIONS TREATMENT

open access: yesИнфекция и иммунитет, 2014
. The immune status and the level of specific antibodies to Cytomegalovirus (121 patients) or Mycoplasma pneumoniae (129 patients) were tested in 250 patients aged 19–56 years old. This cohort was divided for three groups. Seventy eight patients with low
A. P. Toptygina   +2 more
doaj   +1 more source

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

open access: yesAdvanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang   +15 more
wiley   +1 more source

Assay of TORCH profile in patients with congenital cataract aged 0-4 years at a tertiary eye hospital

open access: yesKerala Journal of Ophthalmology
Purpose: To evaluate the TORCH profile (Toxoplasma gondii, rubella, cytomegalovirus, and herpes simplex virus1 and 2) of all patients with congenital cataract excluding traumatic cataracts aged 0-4 yrs over a period 12 months at a tertiary eye hospital ...
K Tejaswi   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy