Results 91 to 100 of about 986,167 (302)

Effects of tACS-Like Electrical Stimulation on Off- and On-Off Center Retinal Ganglion Cells: Part II

open access: yesEye and Brain, 2022
Christianne E Strang, Franklin R Amthor Department of Psychology, The University of Alabama at Birmingham, Birmingham, AL, 35294-1170, USACorrespondence: Franklin R AmthorDepartment of Psychology, The University of Alabama at Birmingham, Birmingham, AL ...
Strang CE, Amthor FR
doaj  

Mdivi-1, a mitochondrial fission inhibitor, modulates T helper cells and suppresses the development of experimental autoimmune encephalomyelitis. [PDF]

open access: yes, 2019
BACKGROUND: Unrestrained activation of Th1 and Th17 cells is associated with the pathogenesis of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis (EAE).
Chai, Zhi   +12 more
core   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle   +11 more
wiley   +1 more source

A single-cell transcriptomic dataset profiling traumatic brain injury and NeuroD1-based gene therapy in mice

open access: yesScientific Data
Traumatic brain injury (TBI), a leading cause of death and disability globally, often results in functional impairments due to complex pathological mechanisms and limited therapeutic options.
Rongjie Chen   +9 more
doaj   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz   +11 more
wiley   +1 more source

Uncovering actionable trade-offs of antifungal resistance in a yeast pathogen

open access: yesMolecular Systems Biology
The increasing prevalence of antifungal resistance represents a major clinical challenge. To explore potential new therapeutic avenues, we investigated fitness trade-offs associated with azole and echinocandin resistance in Nakaseomyces glabratus (syn ...
Juan Carlos Nunez-Rodriguez   +2 more
doaj   +1 more source

What Do Microglia Really Do in Healthy Adult Brain?

open access: yesCells, 2019
Microglia originate from yolk sac-primitive macrophages and auto-proliferate into adulthood without replacement by bone marrow-derived circulating cells.
Marcus Augusto-Oliveira   +7 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

Wheel Running Improves Motor Function and Spinal Cord Plasticity in Mice With Genetic Absence of the Corticospinal Tract

open access: yesFrontiers in Cellular Neuroscience, 2019
Our previous studies showed that mutant mice with congenital absence of the corticospinal tract (CST) undergo spontaneous remodeling of motor networks to partially compensate for absent CST function.
Wei Zhang   +10 more
doaj   +1 more source

Power Efficient and Secure Full-Duplex Wireless Communication Systems

open access: yes, 2015
In this paper, we study resource allocation for a full-duplex (FD) radio base station serving multiple half-duplex (HD) downlink and uplink users simultaneously.
Ng, Derrick Wing Kwan   +2 more
core   +1 more source

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