From Sensing Mechanisms to System Co-Design: Graphene-Based Sensors and Readout Circuits. [PDF]
Zhang J +5 more
europepmc +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Fatigue and Driving Safety in Early Parenthood: Developing Feasible Risk-Reduction Strategies Through Co-Design. [PDF]
Sprajcer M +9 more
europepmc +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Co-Design of a Novel Desirability of Outcome Ranking for Medication Trials in Psychosis. [PDF]
Stainton A +13 more
europepmc +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Algorithm-hardware co-design of neuromorphic networks with dual memory pathways. [PDF]
Sun P +5 more
europepmc +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Victoria [cartographic material]
Map of Victoria showing administrative districts highlighted in different colours.; Plate [2] from: Whitehead's Atlas of Australasia. Melbourne : Published by E.
Whitehead & Co.
core
A Co-Design Methodology for Developing a Training Program for Financial Specialists on Climate Neutrality [PDF]
LAUREA MAGISTRALEQuesta tesi si propone di applicare pratiche di co-design per lo sviluppo di un programma di formazione per specialisti finanziari sulla neutralità climatica.
Garancini, Daniele
core

