Results 181 to 190 of about 7,854,438 (311)

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Parasitic co-infections: challenges and solutions [PDF]

Parasitology, 2008
Mark, Booth, Andrea, Graham, Mark, Viney
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Mycoplasma Pneumonia and Influenza B Co-infection in an Adult. [PDF]

Cureus
Mehta H, Kalantary A, Shafiei S.
europepmc   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Detection of circovirus and herpesvirus co-infection in suddenly dead. [PDF]

Vet Res Commun
Ledwoń A, Sapierzyński R, Dolka B, Witkowska D, Gbylik-Sikorska M, Sell B.   +5 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

The Consequences of Plant Anatomy on Viral Co-Infection

Plant viruses are infectious agents that exploit plants to survive, transmitted from host to host primarily by insect vectors. Within plant hosts, viral populations encounter both physical and physiological barriers that may influence their evolution ...
Hannah Kilford (21065882)
core   +2 more sources

Co-infecção tuberculose/HIV Tuberculosis/HIV co-infection

Jornal Brasileiro de Pneumologia, 2008
Antônio Carlos Moreira Lemos
doaj   +1 more source

Pediatric Systemic Lupus Erythematosus Complicated by Acute EBV and CMV Co-infection. [PDF]

J Clin Lab Anal
Chen A, Ji G, Lan Z, Li P, Wang J, Zhang L, Hu C, Zhang S.   +7 more
europepmc   +1 more source