Results 201 to 210 of about 7,496,605 (313)

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Quadruple co-infection with Mycobacterium tuberculosis complex and M. kansasii in a chronically immunosuppressed cat. [PDF]

Vet Res Commun
Choi S, Choi SN, Lee TG, Ryoo S, Kwak JH, Kim KW, Park TI, Song WJ, Lee EJ, Jeong KS.   +9 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Innate Immune Responses Induced by H9N2 Influenza A Virus and <i>Klebsiella pneumoniae</i> Co-Infection. [PDF]

Viruses
Zhu YJ, Du RR, Xiao F, Shao LY, Sun JX, Zhou YJ, Shi YX, Jin YW, Xie ZJ.   +8 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

A Global Perspective on the Emerging Threat of Zika and Dengue Co-infection. [PDF]

PLoS Negl Trop Dis
Saha A, Anjum M, Labiba SJ, Jaman M, Al Sayed A, Rahat RJ.   +5 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Phenotypic characterization of mucosal-associated invariant T cells in visceral leishmaniasis and HIV co-infection. [PDF]

Front Immunol
Pereira VHS, Nogueira GAF, Borges-Fernandes L, de Carvalho SH, Nogueira AMC, Araújo AL, Brito-de-Sousa JP, Rodrigues JA, Toledo JPRM, Magalhães VCR, de Carvalho JC, da Cunha LF, Coelho-Dos-Reis JGA, Teixeira-Carvalho A, Martins-Filho OA, Guimarães GMC, Peruhype-Magalhães V.   +16 more
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Bacteremic Group A Streptococcal Co-Infection in Two Adults with H3N2 Influenza in Japan, 2025-2026: A Case Series. [PDF]

Int Med Case Rep J
Seki M.
europepmc   +1 more source