Results 61 to 70 of about 7,854,438 (311)

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Handshake stewardship over a decade: refinement after successful implementation

Antimicrobial Stewardship & Healthcare Epidemiology
Objective: To assess anti-infective use after over a decade of handshake stewardship by analyzing days of therapy per thousand patient days for all anti-infectives.
Kira E. Frappa, Matthew J. Weber, Kelly Pearce, Sarah K. Parker   +3 more
doaj   +1 more source

The mechanisms of action of Plasmodium infection against cancer

Cell Communication and Signaling, 2021
Our murine cancer model studies have demonstrated that Plasmodium infection activates the immune system that has been inhibited by cancer cells, counteracts tumor immunosuppressive microenvironment, inhibits tumor angiogenesis, inhibits tumor growth and ...
Xiaoping Chen, Li Qin, Wen Hu, Dickson Adah   +3 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

HIV and Co-Infections: Updates and Insights

Viruses, 2023
Co-infections are frequent in HIV patients; some of them may be AIDS-defining, while others share the same underlying virus mechanism [...]
Francesco Di Gennaro, Alessandra Vergori, Davide Fiore Bavaro   +2 more
openaire   +4 more sources

Immune factors produced by PBMCs upon stimulation with lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1-derived exopolysaccharides inhibit HCoV-229E and SARS-CoV-2 replication

Scientific Reports
The COVID-19 pandemic entered a controllable phase due to vaccine and drug development. The development of defense strategies of enhancing host innate immunity remains imperative to counter the emergence of infectious SARS-CoV-2 variants.
Shuyi Tang, Reiko Takai-Todaka, Shoko Ishii, Hiroki Kono, Reiko Watanabe, Miho Ogawa, Hiroshi Kano, Kazuhiko Katayama, Toshihiro Sashihara, Kenichi Hojo, Kei Haga   +10 more
doaj   +1 more source

Discriminative Index: A Novel Indicator for Evaluating Machine Learning Algorithms in Laboratory Medicine

Diagnostics
Background: Machine learning models are increasingly applied in clinical practice. However, conventional performance metrics such as sensitivity, specificity, and accuracy do not capture the structural characteristics of predictive probability ...
Hsin-Yao Wang, Wan-Ying Lin, Martin Spüler, Sven Brand, Jia-Ruei Yu, Markus Kostrzewa   +5 more
doaj   +1 more source

Barriers Preventing Liver Transplantation in Canadians with HIV Infection – Perceptions of HIV Specialists

Canadian Journal of Gastroenterology, 2007
Liver transplantation is a life-saving procedure with demonstrated utility. There are accumulating data indicating that this procedure is helpful in HIV-infected patients as well.
Curtis L Cooper, Joanne DeForest, John Gill, Richard Lalonde, on behalf of the Canadian HIV Trials Network (CTN) Co-Infection Core Group   +4 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

co-infection data

, 2014
co-infection ...
Chris Newman (230178), Terry Burke (80052), Yung Wa Sin (230192), Sin, Yung Wa, Macdonald, David W., Dugdale, Hannah L., David W. Macdonald (154641), Annavi, Geetha, Hannah L. Dugdale (814756), Newman, Chris, Geetha Annavi (3190065), Burke, Terry   +11 more
core   +1 more source