Results 71 to 80 of about 1,054,030 (246)

Effects of co-processing variables on properties of metronidazole tablets containing co-processed starch as sole excipient

open access: yesJournal of Pharmacy & Bioresources, 2017
Formulation development of pharmaceutical products is often subjected to trials and errors, and to find the best formulary could be time consuming and financially wasteful. Factorial experimental design has been proposed to optimized formulation of pharmaceutical products. In this study a 23 factorial experimental design has been used to quantitatively
Oyeniyi, Yinka J.   +1 more
openaire   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

A Facile Approach for the Preparation of Nano-size Zinc Oxide in Water/Glycerol with Extremely Concentrated Zinc Sources

open access: yesNanoscale Research Letters, 2018
A facile process to prepare zinc oxide (ZnO) nanoparticles from an aqueous zinc chloride (ZnCl2) solution and an aqueous hydroxide solution under a glycerol stabilizer at room temperature was developed. ZnCl2 aqueous solutions as concentrated as 65–80 wt%
Zhiguo Wang   +4 more
doaj   +1 more source

Formulation and Evaluation of Co-Processed Excipient

open access: yesOpen Access Journal of Pharmaceutical Research, 2022
The main purpose of the current review article is to provide a comprehensive overview of the latest developments in assistive technology and the mechanisms involved in the development of those assistants. Architectural scientists have observed that paramedics do not always provide the functionality needed to allow certain active ingredients to be made ...
openaire   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Hydrocarbon-conversion reaction and new paraffin-kinetic model during straight-run gas oil (SRGO) hydrotreating

open access: yesCarbon Resources Conversion
A series of related experiments were carried out based on prepared hydrocracking catalyst, Catalyst-HC. Ni & W and USY molecular sieve were selected as the hydrogenation active component and the cracking component of Catalyst-HC, respectively ...
Kui Zhang   +6 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Embedded slow-release materials for the remediation of organic pollutants in groundwater: A review

open access: yesDesalination and Water Treatment
Groundwater is a critical part of the global water cycle. However, the groundwater around the world has been polluted to varying degrees, with organic pollutants being one of the main sources.
Bing Qin   +8 more
doaj   +1 more source

Simultaneous consumption of cellobiose and xylose by Bacillus coagulans to circumvent glucose repression and identification of its cellobiose-assimilating operons

open access: yesBiotechnology for Biofuels, 2018
Background The use of inedible lignocellulosic biomasses for biomanufacturing provides important environmental and economic benefits for society. Efficient co-utilization of lignocellulosic biomass-derived sugars, primarily glucose and xylose, is ...
Zhaojuan Zheng   +10 more
doaj   +1 more source

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