Results 71 to 80 of about 280,105 (248)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

State Estimation of Drive-by-Wire Chassis Vehicle Based on Dual Unscented Particle Filter Algorithm

Chinese Journal of Mechanical Engineering
Accurate vehicle dynamic information plays an important role in vehicle driving safety. However, due to the characteristics of high mobility and multiple controllable degrees of freedom of drive-by-wire chassis vehicles, the current mature application of
Zixu Wang, Chaoning Chen, Quan Jiang, Hongyu Zheng, Chuyo Kaku   +4 more
doaj   +1 more source

Internal Temperature Estimation of Lithium Batteries Based on a Three-Directional Anisotropic Thermal Circuit Model

World Electric Vehicle Journal
In order to improve the accuracy of internal temperature estimation in batteries, a 10-parameter time-varying multi-surface heat transfer model including internal heat production, heat transfer and external heat transfer is established based on the ...
Xiangyu Meng, Huanli Sun, Tao Jiang, Tengfei Huang, Yuanbin Yu   +4 more
doaj   +1 more source

Determinate composition of FMUs for co-simulation

2013 Proceedings of the International Conference on Embedded Software (EMSOFT), 2013
In this paper, we explain how to achieve deterministic execution of FMUs (Functional Mockup Units) under the FMI (Functional Mockup Interface) standard. In particular, we focus on co-simulation, where an FMU either contains its own internal simulation algorithm or serves as a gateway to a simulation tool.
Broman, David, Brooks, Christopher, Greenberg, Lev, Lee, Edward A., Masin, Michael, Tripakis, Stavros, Wetter, Michael   +6 more
openaire   +3 more sources

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Architectural Concept and Evaluation of a Framework for the Efficient Automation of Computational Scientific Workflows: An Energy Systems Analysis Example

Applied Sciences, 2019
Scientists and engineers involved in the design of complex system solutions use computational workflows for their evaluations. Along with growing system complexity, the complexity of these workflows also increases.
Jianlei Liu, Eric Braun, Clemens Düpmeier, Patrick Kuckertz, D. Severin Ryberg, Martin Robinius, Detlef Stolten, Veit Hagenmeyer   +7 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Highly efficient models and simulations - the basis of design of mechatronic systems [PDF]

Metalurgija, 2010
The paper describes the efficient techniques for assembly of multidisciplinary simulation models and then the efficient techniques for their simulation.
M. Valasek
doaj  

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source