Results 91 to 100 of about 12,604 (184)

Mitochondrial Ca2+ uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain

The Journal of Physiology, EarlyView.
Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray, Girish Halemirle, Beatriz Ferrán, Hadyn Rose, Traci L. Redwine, Sophia Pham, Bo Hagy, Atul Pranay, Jennifer Giorgione, Stacy A. Hussong, Veronica Galvan, Kenneth Humphries, Holly Van Remmen, Mike Kinter, William E. Sonntag, Pankaj K. Singh, Carlos Manlio Díaz‐García   +16 more
wiley   +1 more source

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

Clinical Outcome Prediction Model in Tetralogy of Fallot Without Pulmonary Valve Replacement Using Contraction Fraction From the SCOUT‐TOF Registry

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Few large scale prediction models of clinical outcomes in repaired tetralogy of Fallot (rTOF) exist. Further, contraction fraction, a novel parameter indexing stroke volume by mass reflecting myocardial efficiency, has not been studied.
Mark A. Fogel, Jennifer A. Faerber, Abdullah Mahmood, Keerthi Reddy, Xuemei Zhang, Elizabeth Goldmuntz, Matthew A. Harris, David Biko, Sara Partington, Stephen Paridon, Michael Mcbride, Victor Ferrari, Kevin K. Whitehead, Laura Mercer‐Rosa   +13 more
doaj   +1 more source

Channel Microenvironment‐Controlled Pillared MOF as Efficient Triboelectric Nanogenerator Material for Self‐Powered Degradation of Organic Pollutants

ENERGY &ENVIRONMENTAL MATERIALS, Volume 9, Issue 5, September 2026.
The pore microenvironment regulation of metal–organic framework (MOF) significantly enhanced the output performance of triboelectric nanogenerators (TENG) through SC‐SC transformation, which provides a new idea for the construction of self‐powered degradation systems for organic pollutants.
Long Li, Zhichao Shao, Weibing Liu, Yuchen Liu, Shuhan Zhao, Yi Wei, Jianing Zhang, Xueyou Wang, Hongwei Hou   +8 more
wiley   +1 more source

A multiplex assay to detect mosquito species, bloodmeal host source and Plasmodium in malaria vectors using Nanopore amplicon sequencing

Medical and Veterinary Entomology, Volume 40, Issue 3, Page 465-477, September 2026.
Insectary‐reared mosquitoes were simultaneously assessed for species identification, bloodmeal source analysis and Plasmodium detection, using a single multiplexed sequencing run on the MinION sequencing platform. The method was applied to 150 insectary‐reared mosquitoes, representing nine species blood‐fed with five vertebrate hosts and 40 samples for
E. Abby Rogers, Dieunel Derilus, Christopher Sandi, Lisa Reimer, Audrey Lenhart, Lucy Mackenzie Impoinvil   +5 more
wiley   +1 more source

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

Advanced Science, Volume 13, Issue 44, 7 August 2026.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An, Yunxia Zou, Wenli Wang, Zhimei Cheng, Zhuoxing Zhang, Ruwei Liu, Xiong Wang, Kunlun Huang, Fangrong Ding, Yunping Dai, Qingyong Meng, Yali Zhang   +11 more
wiley   +1 more source

CLRN1 Variants in Müller Cells Cause Mitochondrial Dysfunction in USH3A Retinal Organoids

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
We generated retinal organoids from a patient with USH3A and performed single‐cell RNA sequencing. CLRN1 was specifically expressed in Müller cells, where its variants led to mitochondrial dysfunction and photoreceptor degeneration. ABSTRACT Background Usher syndrome 3A (USH3A), caused by mutations in the CLRN1 gene, leads to retinitis pigmentosa and ...
Rui Zhang, Xinbo Ji, Han Yu, Jingwen Xu, Yu Wang, Ping Sun, Yingxin Wang, Yao Tang, Zexin Zhan, Yichang Jiao, Didi Shan, Pengfei Lin, Dong‐dong Wang, Yuying Zhao, Xianyang Liu, Chuanzhu Yan, Jianqiao Li, Mingfeng Li, Fuchen Liu, Shengping Hou   +19 more
wiley   +1 more source

The Complete Mitochondrial Genome and Phylogenetic Position of the Pacific Spiny Dogfish Squalus suckleyi (Squaliformes: Squalidae)

Ecology and Evolution, Volume 16, Issue 8, August 2026.
The Pacific spiny dogfish (Squalus suckleyi) is a North Pacific shark of conservation consern that until now lacked a complete mitochondrial genome. We report its first mitogenome (16,738 bp; 37 genes), assembled from PacBio HiFi reads and recover it as sister to S.
Laure Inçaby, Sabrina Haney, Michael Phelps, Catherine S. Jones, Marcela Uliano‐Silva, Galice Hoarau, Leslie R. Noble   +6 more
wiley   +1 more source

Assessing Biodiversity in Agricultural Landscapes Through Drone‐Based Environmental DNA Sampling

Ecology and Evolution, Volume 16, Issue 8, August 2026.
We developed a drone‐based environmental DNA (eDNA) swabbing method to assess hexapod diversity in agricultural fields under three management types (conventional, organic, and IP‐Suisse), detecting 75 taxa across 19 families. eDNA replicates showed consistent within‐field results, though no significant differences in diversity were found between ...
Camille Albouy, Louise Humbert, Kerstin Niedermeier, Marc Chautem, Fabian Fopp, Martina Luthi, Sarah Thurnheer, Virginie Marques, Steffen Kirchgeorg, Christian Geckeler, Ali Nasrallah, Stefano Mintchev, Loïc Pellissier   +12 more
wiley   +1 more source

Electrodeposited Cobalt Bis(pyridylimino)isoindolide Complex on Graphite: Synthesis, Characterization, and Electrocatalytic Activity Toward Hydrogen Evolution Reaction

Energy Technology, Volume 14, Issue 8, August 2026.
Cobalt incorporation into a benzimidazole‐based framework transforms its hydrogen evolution performance, delivering enhanced current density, lower overpotential, and faster charge–transfer kinetics. Structural, spectroscopic, morphologic, compositional, and electrochemical analyses reveal a synergistic metal–ligand effect that promotes efficient ...
Selin Gümrükçü, Baran Sarac, Jozef Keckes, Tolga Karazehir, Eray Yüce, Ekrem Kaplan, Radovan Černý, Jürgen Eckert, A. Sezai Sarac, İbrahim Özçeşmeci   +9 more
wiley   +1 more source