Results 11 to 20 of about 883,629 (401)

Prominent changes in blood coagulation of patients with SARS-CoV-2 infection

Clinical Chemistry and Laboratory Medicine, 2020
Background As the number of patients increases, there is a growing understanding of the form of pneumonia sustained by the 2019 novel coronavirus (SARS-CoV-2), which has caused an outbreak in China.
Huan Han, Lan Yang, R. Liu, Fang Liu, Kailang Wu, Jie Li, Xinghui Liu, Chengliang Zhu   +7 more
semanticscholar   +1 more source

COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection

Blood, 2020
Patients with coronavirus disease 2019 (COVID-19) have elevated D-dimer levels. Early reports describe high venous thromboembolism (VTE) and disseminated intravascular coagulation (DIC) rates, but data are limited.
Hanny Al-Samkari, R. K. Karp Leaf, W. Dzik, J. Carlson, Annemarie E. Fogerty, A. Waheed, Katayoon Goodarzi, Pavan K Bendapudi, L. Bornikova, Shruti Gupta, D. Leaf, D. Kuter, R. Rosovsky   +12 more
semanticscholar   +1 more source

Endothelial cells and coagulation

Cell and Tissue Research, 2021
Endothelial cells form a monolayer, which lines blood vessels. They are crucially involved in maintaining blood fluidity and providing controlled vascular hemostasis at sites of injury.
Katharina Neubauer, B. Zieger
semanticscholar   +1 more source

Heparin-induced thrombocytopenia and COVID-19

Hematology Reports, 2021
Heparin-induced thrombocytopenia (HIT) has not been included as a possible cause of thrombocytopenia in Coronavirus Disease 2019 (COVID-19) patients. We report a case of HIT in a patient with COVID-19 treated with heparin.
Michelangelo Sartori, Benilde Cosmi
doaj   +1 more source

Coagulation and non‐coagulation effects of thrombin [PDF]

Journal of Thrombosis and Haemostasis, 2016
Thrombin is a multifunctional serine protease produced from prothrombin, and is a key regulator in hemostatic and non-hemostatic processes. It is the main effector protease in primary hemostasis by activating platelets, and plays a key role in secondary hemostasis.
Henri M. H. Spronk, Jelle J. Posthuma, Jens Posma   +2 more
openaire   +3 more sources

Application of the thrombin generation assay in patients with antiphospholipid syndrome: A systematic review of the literature

Frontiers in Cardiovascular Medicine, 2023
BackgroundThe antiphospholipid syndrome (APS) is classified by the presence of antiphospholipid antibodies (aPL) and thrombotic and/or adverse obstetric outcomes. The diagnosis and risk assessment of APS is challenging.
Rachel Gehlen, Rachel Gehlen, Arne Vandevelde, Arne Vandevelde, Bas de Laat, Bas de Laat, Katrien M. J. Devreese, Katrien M. J. Devreese   +7 more
doaj   +1 more source

Difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2

Journal of Thrombosis and Thrombolysis, 2020
Severe coronavirus disease 2019 (COVID-19) is commonly complicated with coagulopathy, the difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2 has not been analyzed.
Shi-qi Yin, Ming Huang, Dengju Li, N. Tang   +3 more
semanticscholar   +1 more source

Semi-automated thrombin dynamics applying the ST Genesia thrombin generation assay

Frontiers in Cardiovascular Medicine, 2022
BackgroundThe haemostatic balance is an equilibrium of pro- and anticoagulant factors that work synergistically to prevent bleeding and thrombosis.
Audrey Carlo, Qiuting Yan, Qiuting Yan, Hugo Ten Cate, Romy De Laat-Kremers, Romy De Laat-Kremers, Bas De Laat, Bas De Laat, Marisa Ninivaggi   +8 more
doaj   +1 more source

COVID-19-associated coagulopathy and disseminated intravascular coagulation

International journal of hematology, 2020
The pathology of coronavirus disease 2019 (COVID-19) is exacerbated by the progression of thrombosis, and disseminated intravascular coagulation (DIC), and cytokine storms.
H. Asakura, H. Ogawa
semanticscholar   +1 more source

Coagulation and coagulation signalling in fibrosis

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2013
Following tissue injury, a complex and coordinated wound healing response comprising coagulation, inflammation, fibroproliferation and tissue remodelling has evolved to nullify the impact of the original insult and reinstate the normal physiological function of the affected organ.
Paul F. Mercer, Rachel C. Chambers
openaire   +3 more sources