Results 51 to 60 of about 1,007,107 (382)

Coagulation

Journal of the Royal College of Physicians of Edinburgh, 2014
The haemostatic system comprises four compartments: the vasculature, platelets, coagulation factors, and the fibrinolytic system. There is presently no laboratory or near-patient test capable of reproducing the complex regulated interaction between these four compartments. The prothrombin time (PT) and activated partial thromboplastin time (APTT) only
openaire   +2 more sources

Gene transfer in hemophilia B: a big step forward

Bleeding, Thrombosis and Vascular Biology, 2023
Not ...
Giancarlo Castaman
doaj   +3 more sources

DOAC‐Stop in lupus anticoagulant testing: Direct oral anticoagulant interference removed in most samples

Research and Practice in Thrombosis and Haemostasis, 2021
Background The use of direct oral anticoagulants (DOACs) is a convenient therapeutic option for patients at risk of thrombosis. DOACs interfere with clot‐based testing for the identification of lupus anticoagulant antibodies (LACs) in patients with ...
Steven Andrew Baker, Jing Jin, Christopher Pfaffroth, Trang Vu, James L. Zehnder   +4 more
doaj   +1 more source

Diabetes Mellitus and Cardiovascular Prevention: The Role and the Limitations of Currently Available Antiplatelet Drugs

International Journal of Vascular Medicine, 2011
Diabetes mellitus (DM) is associated with macrovascular and microvascular complications. Platelets have a “key role” in atherogenesis and its thrombotic complications in subjects with DM.
A. Tufano, E. Cimino, M. N. D. Di Minno, P. Ieranò, E. Marrone, A. Strazzullo, G. Di Minno, A. M. Cerbone   +7 more
doaj   +1 more source

Impaired platelet function in Hermansky-Pudlak syndrome associated with novel mutations in HPS3, HPS6 and HPS8 genes

Bleeding, Thrombosis and Vascular Biology
We report three unrelated cases of Hermansky-Pudlak (HP) characterized by novel mutations in HPS3 (compound heterozygosity for c.1457G>A and c.1813G>T), HPS6 (homozygous c.210_211insGGGCC), and HPS8 (homozygous c.299dupC in BLOC1S3) genes.
Lisa Pieri, Silvia Linari, Francesca Salvianti, Monica Attanasio, Giancarlo Castaman   +4 more
doaj   +1 more source

Phase transition of the one-dimensional coagulation-production process

, 2000
Recently an exact solution has been found (M.Henkel and H.Hinrichsen, cond-mat/0010062) for the 1d coagulation production process: 2A ->A, A0A->3A with equal diffusion and coagulation rates. This model evolves into the inactive phase independently of the
E. Carlon, G. Mennon, G. Szabó, G. Ódor, G. Ódor, G. Ódor, G. Ódor, G. Ódor, Géza Ódor, H. A. Gutowitz, H. Hinrichsen, H. Hinrichsen, H. Hinrichsen, H. Hinrichsen, H. K. Janssen, I. Jensen, M. Henkel, M. J. Howard, M. Suzuki, N. Menyhárd, N. Menyhárd, P. Grassberger, P. Grassberger, R. Dickman, S. Kwon   +24 more
core   +1 more source

Non-universal scaling and dynamical feedback in generalized models of financial markets [PDF]

, 2002
We study self-organized models for information transmission and herd behavior in financial markets. Existing models are generalized to take into account the effect of size-dependent fragmentation and coagulation probabilities of groups of agents and to ...
Bak, Bannerjee, Chang, Cont, D'Hulst, D'Hulst, D'Hulst, Dafang Zheng, Eguíluz, Farmer, G.J. Rodgers, Gopikrishnan, Lux, Mantegna, Nagel, P.M. Hui, R. D'Hulst, Ramsden, Topol   +18 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Charging and Growth of Fractal Dust Grains

, 2007
The structure and evolution of aggregate grains formed within a plasma environment are dependent upon the charge acquired by the micron-sized dust grains during the coagulation process.
Hyde, Truell W., Matthews, Lorin S.
core   +1 more source

Changes in blood coagulation in patients with severe coronavirus disease 2019 (COVID‐19): a meta‐analysis

British Journal of Haematology, 2020
Coronavirus disease 2019 (COVID-19) is widely spread and poses a critical threat to global health (Zhang et al). Prominent changes in coagulation function in severe patients of COVID-19 have been reported in a recent study (Han, et al 2020).
M. Xiong, Xue Liang, Youdong Wei
semanticscholar   +1 more source