Results 51 to 60 of about 637,976 (296)

Retrotransposon Expression Is Upregulated in Adulthood and Suppressed during Regeneration of the Limb in the Axolotl (Ambystoma mexicanum)

Advanced Biology, EarlyView.
The axolotl's remarkable regenerative abilities decline with age, the causes may include the numerous repetitive elements within its genome. This study uncovers how Ty3 retrotransposons and coexpression networks involving muscle and immune pathways respond to aging and regeneration, suggesting that transposons respond to physiological shifts and may ...
Samuel Ruiz‐Pérez, Nicolás Alcaraz, Karla Torres‐Arciga, José Antonio Ocampo‐Cervantes, Alejandra Cervera, Clementina Castro‐Hernández, Cynthia Gabriela Sámano‐Salazar, Ernesto Soto‐Reyes, Rodrigo González‐Barrios   +8 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

The effect of combined oral contraceptives on thrombin generation assessed on ST Genesia– a paired clinical study

Thrombosis Journal
Background Treatment with combined oral contraceptives (COC) is associated with an increased risk of venous thromboembolism. Several changes of coagulant and anticoagulant factors induced by ethinyloestradiol during treatment with COC, have been ...
Jesper Strandberg, Inger Lise Gade, Jette Nybo, Janus Nikolaj Laust Thomsen, Søren Risom Kristensen   +4 more
doaj   +1 more source

Thrombomodulin is a stronger indicator of combined oral contraceptives-induced activated protein C pathway resistance in the thrombin generation test than activated protein C

Frontiers in Cardiovascular Medicine
BackgroundThe mechanism by which combined oral contraceptives (COCs) lead to hypercoagulation is not fully understood, although activated protein C (APC) pathway resistance has been implicated.
Marisa Ninivaggi, Lily Sokolova, Lily Sokolova, Demy Donkervoort, Bas de Laat, Bas de Laat, Romy de Laat-Kremers   +6 more
doaj   +1 more source

Vaccine-induced thrombosis and thrombocytopenia (VITT) in Ireland: A review of cases and current practices

Thrombosis Update, 2021
Since the beginning of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS CoV-2) virus pandemic, several highly effective and safe vaccines have been produced at remarkable speed. Following global implementation of vaccination programmes, cases of
D. Swan, H. Enright, R. Desmond, G. Le, E. El Hassadi, B. Hennessy, F. Lynott, D. O'Keeffe, M. Crowley, L. Smyth, K. Perera, C. Jennings, F. Ni Ainle, J. Coll, K. Ryan, J. O'Donnell, M. Lavin, N. O'Connell   +17 more
doaj  

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

How I treat disseminated intravascular coagulation.

Blood, 2018
Disseminated intravascular coagulation (DIC) is a condition characterized by systemic activation of coagulation, potentially leading to thrombotic obstruction of small and midsize vessels, thereby contributing to organ dysfunction.
M. Levi, M. Scully
semanticscholar   +1 more source

Preparation and Thermal Modification of Disentangled Ultrahigh‐Molecular‐Weight Polyethylene Particles for Powder‐Based Additive Manufacturing

Advanced Engineering Materials, EarlyView.
Ultrahigh‐molecular‐weight polyethylene powders (<≈40 μm) with a bulk density of 260 g L−1 are prepared from a silica supported bisimine pyridine iron catalyst. The nascent product is disentangled and can be thermally densified without loss of its low viscosity.
Adrian Vaghar, Georgij Jegorenkov, Yunus Kutlu, Andreas Ostendorf, Gerrit A. Luinstra   +4 more
wiley   +1 more source

Viscoelastic Testing in Liver Disease

Annals of Hepatology, 2018
Long thought to be hypocoagulable, new evidence suggests cirrhosis patients have “rebalanced” coagulation in the setting of decreased synthesis of both pro- and anti-coagulant factors. Traditional testing like PT/INR reflects only the decreased synthesis
Jessica P.E. Davis, Patrick G. Northup, Stephen H. Caldwell, Nicolas M. Intagliata   +3 more
doaj  

Sol–Gel Synthesis of Ca2.5Ag0.3Sm0.2Co4O9 Semiconducting Materials for Thermoelectric Applications in Aerospace Systems

Advanced Engineering Materials, EarlyView.
Ca2.5Ag0.3Sm0.2Co4O9 semiconductor materials are synthesized and produced in this study using the sol–gel and cold pressing techniques for thermoelectric generator applications. As template samples are added, the Seebeck coefficient and power factor values rise, peaking at 800 °C for Ca2.5Ag0.3Sm0.2Co4O9 at 274.47 μV K−1 and 0.58 mW mK−2, respectively.
Enes Kilinc, Fatih Uysal, Mucahit Abdullah Sari, Huseyin Kurt, Erdal Celik   +4 more
wiley   +1 more source