Results 61 to 70 of about 1,007,107 (382)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Acute Myeloid Leukemia With NPM1 Mutation Presenting With Rapidly Progressing Hypereosinophilia

Case Reports in Hematology
Hypereosinophilia presents a significant clinical challenge. We describe a case of severe, rapidly progressing hypereosinophilia, with the white blood cell count increasing from 40,000/μL to over 130,000/μL within days, and 70% eosinophils on ...
S. Einarsdottir, G. Orrsjö, L. von Bahr, A. Staffas, L. Fogelstrand   +4 more
doaj   +1 more source

Translation and Cultural Adaptation of the ISTH-Bleeding Assessment Tool to European Portuguese

Acta Médica Portuguesa
Introduction: A distinctive bleeding history is the first diagnostic stage of congenital hemorrhagic diseases. Furthermore, since it is in fact an assessment of the patient’s phenotype, it is not a (mere) complementary diagnostic method or test - it is ...
Diana Carneiro-Leão, Sofia Teixeira, Rita Queirós Pereira, Teresa Mota, Manuela Lopes, Susana Nobre-Fernandes, Fernando Araújo   +6 more
doaj   +1 more source

Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19

Military Medical Research, 2020
Since December 2019, a novel type of coronavirus disease (COVID-19) in Wuhan led to an outbreak throughout China and the rest of the world. To date, there have been more than 1,260,000 COVID-19 patients, with a mortality rate of approximately 5.44 ...
Jing-Chun Song, Gang Wang, Wei Zhang, Yang Zhang, Wei-qin Li, Zhou Zhou   +5 more
semanticscholar   +1 more source

To coagulate or not to coagulate. That is the question

, 2021
Decision-making is a complex issue especially in severe multi-pathological patients, whose processes interact with each other and with other treatments, making it impossible to follow regular protocols. In this case, the patient suffered from a cranioencephalic traumatism and a pulmonary thromboembolism.
de Mota Dengra, Elena, Hidalgo Manchado, Laura, Pérez Villares, José Miguel   +2 more
openaire   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Thiazole orange: a complement to established methods for diagnosing inherited dense granule defects

Platelets
Inherited delta storage pool deficiencies are likely underdiagnosed due to limitations in available diagnostic tools. Achieving accurate diagnosis is thus challenging for clinical laboratories highlighting the need for improved methods.
Myriam Martin, Karin Strandberg, Eva Zetterberg, Eva Norström   +3 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Effect of Escherichia coli endotoxin on Archachatina marginata haemolymph coagulation system [PDF]

, 2010
The effect of _E. coli_ endotoxin on the heamolymph coagulation response of _Archachatina marginata_ was studied. Heamocyte Lysate(HL), Haemocyte Lysate Supernatant(HLS) and Haemocyte Lysate Debris (HLD) were exposed to _Escherichia coli_ endotoxin ...
Adenike Oladiji, Musa Salawu, Musa Yakubu, Nasiru Muhammad, Oyelola Oloyede   +4 more
core   +1 more source

Brownian coagulation and a version of Smoluchowski's equation on the circle

, 2010
We introduce a one-dimensional stochastic system where particles perform independent diffusions and interact through pairwise coagulation events, which occur at a nontrivial rate upon collision. Under appropriate conditions on the diffusion coefficients,
Armendáriz, Inés
core   +1 more source