Results 91 to 100 of about 269,399 (299)

Social Ecology and The Growth Machine Coalition in The Surabaya Policy Dilemma

Journal of Architectural Research and Design Studies, 2019
This study integrates theoretical and analytical approaches of social ecology, urban growth machine, and urban governments. The aim is to explain forms of contrast collaboration between government (political elite) and private developers (local ...
Siti Aminah, A. Hesti Susanti, Roikan Soekartun   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

La vocation redistributive contrariée d’une institution fédérative infranationale. Les faux-semblants du « consensus » partisan à la communauté urbaine de Lille

Lien Social et Politiques, 2006
Les institutions intercommunales françaises ont été créées par le gouvernement à partir de la fin des années 1950, avec pour objectifs annoncés de renforcer l’action publique à l’échelle des agglomérations et de réduire les inégalités territoriales.
Fabien Desage
doaj   +1 more source

Simple Coalitional Games with Beliefs

, 2009
We introduce coalitional games with beliefs (CGBs), a natural generalization of coalitional games to environments where agents possess private beliefs regarding the capabilities (or types) of others.
Chalkiadakis, Georgios, Elkind, Edith, Jennings, Nick   +2 more
core  

Fuzzy coalitional structures (alternatives)

Mathware & soft computing, 2006
The uncertainty of expectations and vagueness of the interests belong to natural components of cooperative situations, in general. Therefore, some kind of formalization of uncertainty and vagueness should be included in realistic models of cooperative behaviour.
Mareš, Milan, Vlach, Milan
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The Fizzling of “Ceboom”: How Jurisdictional Battles and Warring Factions Undermined Cebu's Development Coalition

Journal of Current Southeast Asian Affairs
Starting in the late 1980s, in a phenomenon dubbed “Ceboom,” Cebu City and its surrounding metropolitan area attracted national envy and international attention as a leading centre of growth within a country facing many economic challenges.
Paul D. Hutchcroft, Weena Gera
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source