Improving Pedigree-based Linkage Analysis by Estimating Coancestry Among Families [PDF]
We present a method for improving the power of linkage analysis by detecting chromosome segments shared identical by descent (IBD) by individuals not known to be related. Existing Markov chain Monte Carlo methods sample descent patterns on pedigrees conditional on observed marker data.
Chris Glazner, E. A. Thompson
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Inbreeding, effective population size, and coancestry in the Latxa dairy sheep breed [PDF]
Traditionally, breeding programs have estimated and managed inbreeding based on pedigree information. The availability of genomic marker panels has made possible new alternatives to achieve more precise estimates, for example in case of missing pedigree.
I. Granado-Tajada +3 more
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Estimation of effective number of breeders from molecular coancestry of single cohort sample [PDF]
AbstractThe effective population size, Ne, is an important parameter in population genetics and conservation biology. It is, however, difficult to directly estimate Ne from demographic data in many wild species. Alternatively, the use of genetic data has received much attention in recent years.
Tetsuro Nomura
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Estimating Population-Level Coancestry Coefficients by an Admixture F Model [PDF]
Abstract In this article, we develop an admixture F model (AFM) for the estimation of population-level coancestry coefficients from neutral molecular markers. In contrast to the previously published F model, the AFM enables disentangling small population size and lack of migration as causes of genetic differentiation behind a given level
Markku Karhunen, Otso Ovaskainen
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Inbreeding, Coancestry, and Founding Clones of Sweet Cherries from North America [PDF]
Inbreeding and coancestry coefficients were calculated for 66 sweet cherry (Prunus avium L.) selections released from four breeding programs in North America (HRIO, Vineland, Ont., IAREC, Prosser, Wash., NYSAES, Geneva, N.Y., and PARC, Summerland, B.C.).
Cheol Choi, Frank Kappel
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Drawing inferences about the coancestry coefficient [PDF]
The coancestry coefficient, also known as the population structure parameter, is of great interest in population genetics. It can be thought of as the intraclass correlation of pairs of alleles within populations and it can serve as a measure of genetic distance between populations.
Suvajit Samanta +2 more
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Ratio between inbreeding and coancestry rates as a measure of population subdivision. Preliminary results. [PDF]
Ponencia publicada en ITEA, vol. 104Uno de los factores que provocan incrementos de consanguinidad superiores a los que se esperarían en función del tamaño de la población es la subdivisión de las poblaciones. La medida de la subdivisión de poblaciones
I. Cervantes +3 more
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Small-sized animal populations can undergo significant loss of genetic variability that can lead to their extinction. Therefore, studies on animal breeding have focused on mating systems for minimizing the disappearance of genetic variability.
Candela Ojeda-Marín +4 more
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Genome-wide estimates of coancestry and inbreeding in a closed herd of ancient Iberian pigs. [PDF]
Maintaining genetic variation and controlling the increase in inbreeding are crucial requirements in animal conservation programs. The most widely accepted strategy for achieving these objectives is to maximize the effective population size by minimizing
María Saura +6 more
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Inferring Coancestry in Population Samples in the Presence of Linkage Disequilibrium [PDF]
Abstract In both pedigree linkage studies and in population-based association studies there has been much interest in the use of modern dense genetic marker data to infer segments of gene identity by descent (ibd) among individuals not known to be related, to increase power and resolution in localizing genes affecting complex traits.
Michael D. Brown +3 more
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