Results 41 to 50 of about 118,538 (294)

Labrador retrievers under primary veterinary care in the UK: demography, mortality and disorders [PDF]

open access: yes, 2018
Background Labrador retrievers are reportedly predisposed to many disorders but accurate prevalence information relating to the general population are lacking.
A Agresti   +62 more
core   +4 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Genetic effects on coat colour in cattle: dilution of eumelanin and phaeomelanin pigments in an F2-Backcross Charolais × Holstein population

open access: yesBMC Genetics, 2007
Background In cattle, the gene coding for the melanocortin receptor 1 (MC1R) is known to be the main regulator of the switch between the two coat colour pigments: eumelanin (black pigment) and phaeomelanin (red pigment).
Wiener Pamela   +2 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

MC1R gene: comparison between different farm animal species

open access: yesItalian Journal of Animal Science, 2010
Coat colour genes in farm animals have only been studied at molecular level over the last ten years, starting with Klungland et al. in 1995. Among the genes involved in pigmentation, MC1R, previously known as Extension locus, revealed polymorphisms ...
M. Marilli, F. Fornarelli, P. Crepaldi
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

First contribute to the characterization of coat in Lepus corsicanus and Lepus europaeus by colorimetric determinations

open access: yesItalian Journal of Animal Science, 2010
Thetrial wascarriedout on12sympatricadult females: 6Italianhares(Lepus Thetrial wascarriedout on12sympatricadult females: 6Italianhares(Lepus trial was carried out on 12 sympatric adult females: 6 Italian hares (Lepus corsicanus) and 6 Brown hares (Lepus
Pierangelo Freschi   +4 more
doaj   +1 more source

The coding sequence of the ASIP gene is identical in nine wild-type coloured cattle breeds [PDF]

open access: yes, 2011
The aim of this study was to ascertain the role of the Agouti signaling peptide (ASIP) gene coding region in the Agouti locus variation within wild-type coat colour in cattle.
Arranz, J.J. (J.)   +5 more
core  

Corrosion Resistance of Steel/Zinc with Silicate Nanoparticles/Polyurethane Paint Systems in NaCl Solution [PDF]

open access: yes, 2012
Surface characteristics and corrosion behaviour of bare electrogalvanized steel coated with polymer/nano-silicate particles added to the electrogalvanizing bath were studied by scanning electron microscopy (SEM), energy dispersive spectrometer (EDXS) and
Di Sarli, Alejandro Ramón   +2 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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