Results 51 to 60 of about 19,836 (289)

Transport vesicles: Coats of many colours [PDF]

Current Biology, 1998
Clathrin-coated vesicles transport proteins and membranes between intracellular compartments. Adaptor molecules determine vesicle specificity; recently, a third type of adaptor protein, AP3, has been identified and implicated in the biogenesis of endosomal and lysosome-related organelles.
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Table3_Genetics of Base Coat Colour Variations and Coat Colour-Patterns of the South African Nguni Cattle Investigated Using High-Density SNP Genotypes.docx

, 2022
Nguni cattle are a Sanga type breed with mixed B. taurus and B. indicus ancestry and proven resistance to ticks, diseases and other harsh conditions of the African geographical landscape.
Gábor Mészáros (413177), Langelihle Mbali Kunene (12805010), Edgar Farai Dzomba (8803619), Farai Catherine Muchadeyi (8803622), Khanyisile Hadebe (8803613), Trevor Dugmore (12805013), Johann Sölkner (224465)   +6 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Table5_Genetics of Base Coat Colour Variations and Coat Colour-Patterns of the South African Nguni Cattle Investigated Using High-Density SNP Genotypes.pdf

, 2022
Nguni cattle are a Sanga type breed with mixed B. taurus and B. indicus ancestry and proven resistance to ticks, diseases and other harsh conditions of the African geographical landscape.
Gábor Mészáros (413177), Langelihle Mbali Kunene (12805010), Edgar Farai Dzomba (8803619), Farai Catherine Muchadeyi (8803622), Khanyisile Hadebe (8803613), Trevor Dugmore (12805013), Johann Sölkner (224465)   +6 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

The Analysis of Partial Sequences of the Flavonone 3 Hydroxylase Gene in Lupinus mutabilis Reveals Differential Expression of Two Paralogues Potentially Related to Seed Coat Colour

Agronomy, 2022
Flavonone 3 hydroxylases (EC 1.14.11.9) are key enzymes in the synthesis of anthocyanins and other flavonoids. Such compounds are involved in seed coat colour and stem pigmentation.
Norberto Guilengue, Helena G. Azinheira, Sofia Alves, João Neves-Martins, Pedro Talhinhas, Leonor Morais-Cecílio   +5 more
doaj   +1 more source

Table4_Genetics of Base Coat Colour Variations and Coat Colour-Patterns of the South African Nguni Cattle Investigated Using High-Density SNP Genotypes.docx

, 2022
Nguni cattle are a Sanga type breed with mixed B. taurus and B. indicus ancestry and proven resistance to ticks, diseases and other harsh conditions of the African geographical landscape.
Gábor Mészáros (413177), Langelihle Mbali Kunene (12805010), Edgar Farai Dzomba (8803619), Farai Catherine Muchadeyi (8803622), Khanyisile Hadebe (8803613), Trevor Dugmore (12805013), Johann Sölkner (224465)   +6 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

DataSheet1_Genetics of Base Coat Colour Variations and Coat Colour-Patterns of the South African Nguni Cattle Investigated Using High-Density SNP Genotypes.PDF

, 2022
Nguni cattle are a Sanga type breed with mixed B. taurus and B. indicus ancestry and proven resistance to ticks, diseases and other harsh conditions of the African geographical landscape.
Gábor Mészáros (413177), Langelihle Mbali Kunene (12805010), Edgar Farai Dzomba (8803619), Farai Catherine Muchadeyi (8803622), Khanyisile Hadebe (8803613), Trevor Dugmore (12805013), Johann Sölkner (224465)   +6 more
core   +1 more source