Results 41 to 50 of about 90,378 (260)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Development of yellow seeded brown sarson (Brassica rapa L.) genotypes for temperate conditions of Kashmir [PDF]
Electronic Journal of Plant Breeding, 2012 The inheritance of yellow seed coat-colour in brown sarson (Brassica rapa L.) was investigated in two crosses involvingtwo brown sarson cultivars viz Gulchin and KOS-1 and a yellow seeded genotype Yellow Sarson-1.The segregatingpattern of seed coat ...
A. G. Rather, F. A. Sheikh, S.Najeeb,M. A. Zargar, G. A. Parray, A.B.Shikari, M.A.Ahangar, Z.A.Bhat and Sajad Ahmad
doaj
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
BMC Research Notes, 2012 Background While seed biology is well characterized and numerous studies have focused on this subject over the past years, the regulation of seed coat development and metabolism is for the most part still non-elucidated.
Renouard Sullivan +5 more
doaj +1 more source
Inhibition of Tongue Coat and Dental Plaque Formation by Stabilized Chlorine Dioxide Vs Chlorhexidine Mouthrinse: A Randomized, Triple Blinded Study [PDF]
Journal of Clinical and Diagnostic Research, 2015 Background: Chlorine dioxide (ClO2 ) is an oxidizing agent with known bactericidal, viricidal and fungicidal properties. Its efficacy in reducing the halitosis has been established by previous literature.
Seema Roodmal Yadav +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
MÉTODOS PARA SUPERAÇÃO DA DORMÊNCIA EM SEMENTES DE Garcinia gardneriana (Planch. & Triana) Zappi
Ciência Florestal, 2018 Garcinia gardneriana is a native tree species of the Atlantic Forest biome with commercial potential, industrial application, medicinal, ornamental and timber, which seeds have difficulties on germination.
Ana Patrícia Rocha +4 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source