Results 61 to 70 of about 90,378 (260)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Body weight and white coat hypertension

open access: yes, 2009
Objective: To understand prognostic significance of white coat hypertension (WCH), and any its association with excess weight. Methodology: We studied consecutive check up patients between the ages of 35 and 70 years to be able to see possible consequences of excess weight on health and to avoid debility induced weight loss in elderly people.
Helvaci, Mehmet Rami   +3 more
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Identification of Albizia lebbeck seed coat chitin-binding vicilins (7S globulins) with high toxicity to the larvae of the bruchid Callosobruchus maculatus

open access: yesBrazilian Journal of Medical and Biological Research, 2012
Seed coat is a specialized maternal tissue that interfaces the embryo and the external environment during embryogenesis, dormancy and germination. In addition, it is the first defensive barrier against penetration by pathogens and herbivores.
A.J. Souza   +7 more
doaj   +2 more sources

DESEMPENHO E RESPOSTAS ADAPTATIVAS DE NOVILHOS ANGUS X NELORE EM CLIMA TROPICAL

open access: yesRevista Caatinga, 2015
The aim of this study was to evaluate the performance and the adaptive profile of de 25 steers ¶ Angus x μ Nelore (RED) and 25 steers ´ Angus x ´ Nelore (NEL), during the milking and the fattening phas-es, in an intensive system, at Rio Grande do Norte ...
DÉBORA ANDRÉA EVANGELISTA FAÇANHA   +4 more
doaj  

«On the Coats of Arms of the City of Merida» by B. Moreno de Vargas (17th century) [PDF]

open access: yesЛатиноамериканский исторический альманах
In the heraldic treatise of B. Moreno de Vargas' «Discursos de la nobleza de España», one chapter is devoted to the coat of arms of his hometown, Mérida. Moreno de Vargas favored not the medieval coat of arms of Mérida, but, in keeping with the tradition
Tchernik Alexander
doaj   +1 more source

The Technology of Measurement and Control for Coat Weight.

open access: yesJAPAN TAPPI JOURNAL, 2002
Coated Paper needs have been wide and rich in variety in Japan. That is why the paper coating process and operation became more severe on quality and productivity.In B/M 9000 CS-our newest QCS products introduced in 1998-, we have provided solutions for it, which are three methods to measure Coat Weight and applications for quality control of cross ...
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Heat tolerance index, food intake and weight gain of Santa Ines sheep in the agreste region of Pernambuco State, Brazil - doi: 10.4025/actascianimsci.v35i3.18466

open access: yesActa Scientiarum: Animal Sciences, 2013
This study evaluated the influence of coat color on the heat tolerance and performance of 21 Santa Inês lambs, non-pregnant, non-lactating, seven animals of each coat color: black, brown and white, with an average initial weight of 25.71, 24.85 and 25.00
Florisval Protásio Silva Filho   +5 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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