Results 31 to 40 of about 693,768 (315)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Influence of Molybdenum Addition on the Structure, Mechanical Properties, and Cutting Performance of AlTiN Coatings

open access: yesLubricants
Though AlTiN coating has been intensively studied, there is still a need to develop AlTiN coating to meet the growing demand of industrial machining. One effective way to improve the performance of AlTiN coating is by adding alloying elements.
Tao Yang   +11 more
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

INCREASING EFFICIENCY OF REPAIRING, MANUFACTURING AND OPERATION OF THE TPP FACILITIES BY TECHNOLOGY OF GAS-THERMAL COATING AND LASER SURFACE MELTING

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2015
The article considers effectiveness increase of the TPP heat-mechanical equipment repair, manufacturing and maintenance as exemplified by gas-thermal technique for hardening laststages rotor blades of the steam turbines.
O. E. Grachev   +2 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Design and evaluation of multilayer Yb4Hf3O12-based T/EBCs with enhanced thermal stability for high-temperature applications

open access: yesJournal of Advanced Ceramics
Thermal/environmental barrier coatings (T/EBCs) systems are regarded as potential solutions to address the degradation challenges of ceramic matrix composites (CMCs) under extreme temperatures in aeroengine applications.
Yiming Wu   +6 more
doaj   +1 more source

Recent Development of Electrolyte Engineering for Sodium Metal Batteries

open access: yesBatteries, 2022
Intermittent renewable energy requires a powerful energy storage system to smoothen the relationship between power generation and power consumption. Due to the rapidly rising price of Li resources, the development of Li-ion batteries (LIBs) has been ...
Yingying Ji, Jiabao Li, Jinliang Li
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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