Results 121 to 130 of about 1,339,183 (353)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Advanced coatings through pulsed magnetron sputtering [PDF]

, 2004
Pulsed magnetron sputtering (PMS) has become established as the process of choice for the deposition of dielectric materials for many applications. The process is attractive because it offers stable arc free operating conditions during the deposition
Arnell, RD, Hisek, J, Kelly, PJ, Pilkington, RD, Zhou, Y   +4 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Microstructure, mechanical properties and corrosion behavior of high-entropy (WZrNbTaM)C (M= Cr, Ni, Ti) carbides

Journal of Materials Research and Technology
In this work, the high-entropy stability is predicted based on density functional theory (DFT) firstly. Then, the (WZrNbTaM)C (M = Cr, Ni, Ti) high-entropy carbide powders are synthesized by carbothermal reduction reaction.
Jiatai Zhang, Weili Wang, Zhixuan Zhang, Sijie Wei, Qiang Zhang, Zongyao Zhang, Weibin Zhang   +6 more
doaj   +1 more source

Use of polyethylene glycol coatings for optical fibre humidity sensing [PDF]

, 2008
Humidity induced change in the refractive index and thickness of the polyethylene glycol (PEG) coatings are in situ investigated for a range from 10 to 95%, using an optical waveguide spectroscopic technique.
B. D. Gupta, Bukem Bilen, C. Ronot, D. C. Bownass, E. Kretschmann, F. J. Arregui, F. S. Damos, G. H. Cross, G. Tae, Gulen Aktas, J. H. Seinfeld, K. L. A. Chan, M. Biesalski, M. N. Weiss, Mehmet Naci Inci, Mustafa Muamer Demir, O. Erdamar, P. Kronenberg, R. Jindal, R. Ulrich, S. J. Glenn, S. K. Shukla, S. McMurtry, S. Muto, S. Otsuki, Sabriye Acikgoz, T. M. Aminabhavi, W. L. Chen, Yani Skarlatos, Yusuf Ziya Menceloglu, Z. A. Ansari, Z. M. Rittersma   +31 more
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Recent advances in harnessing biolubricants to enhance tribological performance and environmental responsibility – Bibliometric review (2015–2024)

Cleaner Engineering and Technology
The necessity of conducting research on biolubricants arises from the urgent need to develop sustainable alternatives to conventional petroleum-based lubricants, which contribute to environmental degradation and carbon emissions.
Agus Nugroho, Muhammad Kozin, Zhang Bo, Rizalman Mamat, Mohd Fairusham Ghazali, Muhammad Prisla Kamil, Prabowo Puranto, Diah Ayu Fitriani, Siti Amalina Azahra, Kusuma Putri Suwondo, Putri Sayyida Ashfiya   +10 more
doaj   +1 more source

Moisture-resistant baffle material for fuel tanks [PDF]

, 1974
Test results indicated superiority of certain polyether-based polyurethanes as protective coatings and suggested that baffle-materials with one of these coatings should have useful life approximately twice that of uncoated foams now in ...
Bilow, N.
core   +1 more source

Microstructures and properties of high-entropy alloy films and coatings: a review

, 2018
In the past 14 years, as a branch of high-entropy alloy (HEA) materials, HEA films and coatings have exhibited the attractive and unique properties, relative to the conventional film and coating materials. The recent research and development of HEA films
Wei Li, Ping Liu, P. Liaw
semanticscholar   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source