Results 21 to 30 of about 106,004 (265)
UV-durable self-cleaning coatings for autonomous driving
A key technology to ensure the safety and accuracy of autonomous driving for future transportation is the cleanliness of the sensor surfaces for accurate signal reading.
Songwei Lu +2 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Crack source and propagation of AZ91-0.9Gd alloy
Formation process of main compounds in AZ91-0.9Gd alloy was studied, and main crack sources and fracture mechanism were analyzed. Experimental results show that AZ91-0.9Gd alloy is mainly composed of α-Mg, Mg17Al12, bulk Al2Gd compound and a small amount
Huisheng Cai +5 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The rapidly developing demand for lightweight portable electronics has accelerated advanced research on self-powered microsystems (SPMs) for peak power energy storage (ESs).
Apurba Ray, Jenny Roth, Bilge Saruhan
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Flexible pressure sensors are pivotal in advancing wearable technologies, particularly in human health monitoring. However, the development of high‐performance pressure sensors is challenged by the intrinsic trade‐offs among precision, sensitivity, and ...
Tianyu Zhu +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source

