Results 41 to 50 of about 376,949 (250)

Physical and Tribological Properties of Nitrided AISI 316 Stainless Steel Balls

open access: yesMATEC Web of Conferences, 2016
AISI 316 austenitic stainless steel balls (diameters 5.0 and 12.0 mm, typical hardness 250 HV0.3) and flat samples (20×20×2.0 mm) were nitrided by a pulsed glow discharge Ar/N2 plasma. Hardness of the ball surfaces was analysed using Vickers indentation.
Yang Shicai   +4 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Acknowledgement to Reviewers of Coatings in 2013

open access: yes, 2014
The editors of Coatings would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2013.
Coatings Editorial Office
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

THEORETICAL STUDIES OF THERMAL PROCESSES IN ELECTROLYTIC-PLASMA HARDENING

open access: yesШәкәрім университетінің хабаршысы: Техника ғылымдар
This article examines the theoretical aspects of thermal processes occurring during electrolytic-plasma hardening (EPH), including the analysis of temperature fields and heating rates.
B. Rakhadilov   +4 more
doaj   +1 more source

Effect of empty fruit bunches microcrystalline cellulose (MCC) on the thermal, mechanical and morphological properties of biodegradable poly (lactic acid) (PLA) and polybutylene adipate terephthalate (PBAT) composites

open access: yesMaterials Research Express, 2020
Nowadays, awareness of the environment is rising among society. Thus, more researches on the utilization of biodegradable polymer as an alternative to non-biodegradable polymers have been published. Among various biopolymers, Poly (lactic acid) (PLA) and
A Nor Amira Izzati   +5 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

The use of Highly Ionized Pulsed Plasmas for the Synthesis of Advanced Thin Films and Nanoparticles

open access: yesKONA Powder and Particle Journal, 2014
Pulsed plasma processes open up the possibility of using very high plasma densities and modulated deposition in the synthesis of thin films and nanoparticles.
Iris Pilch   +3 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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