Results 61 to 70 of about 290,782 (316)

The Effect of Electrolytic-Plasma Hardening Time on the Microstructure, Hardness, and Corrosion Behavior of Medium-Carbon Steel

open access: yesCrystals
This study investigates the effect of electrolytic-plasma hardening time on the microstructure formation, hardness distribution, and corrosion behavior of grade 45 structural steel.
Yeldos Mukhametov   +6 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Degradation of Environmental Protection Coatings for Gas Turbine Materials [PDF]

open access: yes, 2008
Nowadays, problems of component materials reliability in gas and oil-fired gas turbines focus on assessing the potential behaviour of commonly employed coatings, in order to avoid expensive and unpredictable failure in service and producing new materials
Nalin, Laura
core  

Micro milling performance assessment of diamond-like carbon coatings on a micro-end mill [PDF]

open access: yes, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2013 Institution of Mechanical Engineers.In micro milling, unpredictable tool life and premature tool failures are the major constraints ...
Cheng, K, Wu, T
core   +1 more source

Investigation of target erosion profiles sputter-eroded by a low-energy broad ion beam

open access: yesAIP Advances, 2021
The demand for ion beam sputtering (IBS) coated substrates is growing. In order to find new fields of application for IBS coating technology, it is necessary to understand in detail the distributions of the involved particles in an industrial-scale ...
Wjatscheslaw Sakiew   +2 more
doaj   +1 more source

The Spore Coat

open access: yesMicrobiology Spectrum, 2016
ABSTRACT Spores of Clostridiales and Bacillales are encased in a complex series of concentric shells that provide protection, facilitate germination, and mediate interactions with the environment.
Adam, Driks, Patrick, Eichenberger
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Improvement in tribological properties of HVOF sprayed WC–Co coatings using electroless Ni–P coated feedstock powders

open access: yes, 2018
The aim of this research is to investigate the sliding friction and wear behavior of a novel WC-Co thermal spray coating deposited from electroless Ni-P coated WC-12Co feedstock powders.
Jafari, M   +4 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

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