Results 91 to 100 of about 19,992,265 (173)

Suspected hyperthyroidism‐associated myoclonus in a cat

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 10‐year‐old, male, neutered domestic shorthair cat presented with a 2‐week history of progressively worsening myoclonic jerks predominantly involving the head. Jerks were continuous and marked at rest, but became less intense during activity.
Magdalena Maria Dyrka, Ian Ramsey, Fiona May Keir James, Grace Kadler, Jessica Zilli, Rodrigo Gutierrez Quintana   +5 more
wiley   +1 more source

Do not Miss Rare and Treatable Cause of Early-Onset Hemolytic Uremic Syndrome: Cobalamin C Deficiency

, 2019
The most common disorder of vitamin B12 metabolism is methylmalonic aciduria and homocystinuria type cobalamin C (cblC), which accounts for most of the cases is referred to as cblC deficiency.
TOPALOĞLU, REZAN, Inozu, Mihriban, COŞKUN, TURGAY, GÜLHAN, BORA, TALİM, BERİL, BİLGİNER GÜRBÜZ, BERRAK   +5 more
core   +1 more source

Body Composition Remodelling During GLP‐1‐Based Therapy: A Systematic Review and Meta‐Analysis Using a Hierarchical Physiological Framework

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9849-9860, November 2026.
ABSTRACT Background Body composition changes during glucagon‐like peptide‐1 (GLP‐1)‐based therapy remain incompletely characterized, particularly regarding their effects on adiposity, muscle quantity, and muscle quality. We conducted a systematic review and meta‐analysis using a predefined physiological framework to evaluate body composition ...
Maria Luizza Lopes Menezes, Maria Eduarda Güntzel Chiappa, Rodrigo Fuentes Kloss, Marcelo Tuesta, Paula Santos, Alberto Souza Sá Filho, Gaspar R. Chiappa   +6 more
wiley   +1 more source

The regulatory roles of liver and kidney in cobalamin (vitamin-B(12)) metabolism in the rat: the uptake and intracellular binding of cobalamin and the activity of the cobalamin-dependent enzymes in response to varying cobalamin supply

, 1984
To examine possible regulatory roles of liver and kidney in cobalamin metabolism, specific activities of the two cobalamin-dependent enzymes, uptake in vivo of cyano [57Co]cobalamin [( 57Co]CNCbl) and the binding of [57Co]Cbl to intracellular proteins ...
Treston, A.M., Cooksley, W.G.E., Bowman, E.P.W., Owens, J.A., Scott, J.S.D.   +4 more
core   +1 more source

Cobalamin deficiency in dogs and cats [PDF]

, 2018
Cobalamin is a member of the B-group of vitamins and a cofactor for metabolic processes like nucleic acid synthesis, amino acid synthesis, and the citric acid cycle.
Toresson, Linda, Spillmann, Thomas, Hanisch, Franziska   +2 more
core   +1 more source

Vitamin B12‐Functionalized Nanogels for pH‐, and Redox‐Responsive Doxorubicin Delivery

ChemBioChem, Volume 27, Issue 20, 28 October 2026.
A polymerizable 5′‐modified vitamin B12‐monomer enables the covalent incorporation of B12 into pH‐ and redox‐responsive nanogels for targeted doxorubicin delivery. The nanogels exhibit glutathione‐triggered drug release, potent antiproliferative activity against HT‐29 cancer cells, and strongly reduced cytotoxicity toward healthy cells.
Serife Dagdelen, Paula D. Mestizo, Marcin Mackiewicz, Agnieszka Kurdyn, Ewa Augustin, Marcin Karbarz, Felix Zelder   +6 more
wiley   +1 more source

Mild clinical features of isolated methylmalonic acidemia associated with a novel variant in the MMAA gene in two Chinese siblings

BMC Medical Genetics, 2018
Background Methylmalonic acidemia (MMA) is an autosomal recessive inherited disorder caused by complete or partial deficiency of the enzyme methylmalonyl-CoA mutase (mut0 enzymatic subtype or mut– enzymatic subtype, respectively); a defect in the ...
Yiming Lin, Chunmei Lin, Weihua Lin, Zhenzhu Zheng, Mingya Han, Qingliu Fu   +5 more
doaj   +1 more source

Characteristics of clinical manifestations and molecular genetics of inherited hyperhomocysteinemia in children and adolescents: a single center experience from China

Frontiers in Neurology
Introduction:Accurate identification of the genetic cause of inherited hyperhomocysteinemia (HHcy) is essential for targeted therapies and individualized treatment. However, reported cases in China remain limited.
Rui Qu, Aimin Han, Yang Zhao, Xiangju Qu, Yali Zhu   +4 more
doaj   +1 more source

Pearls & Oy-sters: Late-Onset Cobalamin C Deficiency Presenting With Subacute Combined Degeneration. [PDF]

Neurology, 2023
Goyne C, Kansal L.
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, Volume 16, Issue 10, Page 1911-1924, October 2026.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source