Results 81 to 90 of about 19,992,265 (173)

Cobalamin Deficiency May Induce Astrosenescence—An In Vitro Study

, 2022
Cobalamin (vitamin B12) deficiency is one of the major factors causing degenerative changes in the nervous system and, thus, various neurological and psychiatric symptoms.
Dorota Wrześniok, Kowalska, Justyna, Wrześniok, Dorota, Rok, Jakub, Zuzanna Rzepka, Rzepka, Zuzanna, Klaudia Banach, Justyna Kowalska, Jakub Rok, Banach, Klaudia   +9 more
core   +1 more source

Retrospective evaluation of outcomes in dogs with non‐associative immune‐mediated haemolytic anaemia treated with rivaroxaban as a sole or adjunctive thromboprophylaxis agent: 34 cases (2018‐2024)

Journal of Small Animal Practice, EarlyView.
Objectives To describe clinical outcomes, thromboembolic and haemorrhagic complications, and treatment characteristics in dogs with non‐associative immune‐mediated haemolytic anaemia treated with rivaroxaban at a UK referral hospital. Materials and Methods Retrospective descriptive study of dogs diagnosed with non‐associative immune‐mediated haemolytic
S. Conway, L. Jenkins, J. Reeve
wiley   +1 more source

Mapping the omics landscape for peri‐implant diseases: A scoping review

Periodontology 2000, EarlyView.
Abstract Objectives To map omics evidence across peri‐implant health, peri‐implant mucositis, and peri‐implantitis, and to identify recurring molecular patterns and candidate biomarker signals relevant to diagnosis, monitoring, and treatment. Materials and Methods This scoping review included human studies using genomics, DNA methylation–based ...
Ethan Ng, Ioannis Fragkioudakis, Jeniffer Perussolo, John Rong Hao Tay, Elena Calciolari, Nikos Donos   +5 more
wiley   +1 more source

Cobalamin deficiency in children: A literature review

, 2013
Objective: The aim of this review is to present cobalamin deficiency in children with a specific focus on infants. Background: Cobalamin deficiency is caused by inadequate intake, malabsorption or inborn errors of vitamin B12 metabolism.
Moen, Synne Helland
core  

Cobalamin deficiency resulting in a rare haematological disorder: a case report [PDF]

, 2009
Introduction We present the case of a patient with a cobalamin deficiency resulting in pancytopaenia, emphasizing the importance to define, diagnose and treat cobalamin deficiency. Case presentation A 52-year-old man from the Democratic Republic of Congo
Favrat Bernard, Bodenmann Patrick, Thomas M Chapuis, Patrick Bodenmann, Chapuis, T.M., Favrat, B., Bernard Favrat, Chapuis Thomas M, Bodenmann, P., Favrat B, Chapuis TM, Bodenmann P   +11 more
core   +2 more sources

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

Vitamin B12 deficiency in a young male with Imerslund-Gräsbeck syndrome: case report

Frontiers in Pediatrics
Imerslund-Gräsbeck syndrome (IGS) is a rare genetic disorder characterized by selective vitamin B12 deficiency co-existing with asymptomatic proteinuria.
Lina Xing, Yujie Guo, Yang Li, Xuquan Zhou, Fengru Lin, Yan Wang   +5 more
doaj   +1 more source

Relationships among nitrous oxide exposure, neurological injury and biomarkers

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3959-3971, November 2026.
Aims Recreational nitrous oxide (N2O) misuse is an increasing public health problem associated with functional cobalamin (B12) deficiency and severe neurological complications. Despite growing recognition of its harms, the dose–response relationship and clinical value of biomarkers remain unclear.
Laxna Bhujel, Angela L. Chiew, Bhashita Jagarlamudi, Pramod Chandru, Naren Gunja, Nancy Briggs, Betty S. Chan   +6 more
wiley   +1 more source

Reliable and powerful laboratory markers of cobalamin deficiency in the newborn: plasma and urinary methylmalonic acid

, 2016
Background: Diagnosing cobalamin deficiency is critical, given the high prevalence of cobalamin deficiency particularly in developing countries. Measuring serum cobalamin levels is of limited diagnostic sensitivity, in other words its specificity and ...
Kirecci, Ahmet, İŞLEK, Ali, KALAY, Salih, Kalay, Zuhal, KOKLU, Esad, PARLAK, Mesut, GUNEY, Ozgur   +6 more
core   +1 more source

Refining MMA Screening in the Dutch Newborn Screening Program: Lessons from Vitamin B12 Deficiency and Genetic Cases

International Journal of Neonatal Screening
Since October 2019, screening for methylmalonic acidemia (MMA) has been implemented in the Dutch Newborn Screening (NBS) program. Since implementation, most referrals for MMA have been the result of (maternal) vitamin B12 deficiency. Although vitamin B12
Nils W. F. Meijer, Klaas Koop, Rose E. Maase, Patricia L. Hall, Wouter F. Visser, Esmeralda Oussoren, Annet M. Bosch, M. Rebecca Heiner-Fokkema, Monique G. M. de Sain-van der Velden   +8 more
doaj   +1 more source