Results 11 to 20 of about 424,865 (327)

Development of a Broad-Spectrum Antiserum against Cobra Venoms Using Recombinant Three-Finger Toxins

open access: yesToxins, 2021
Three-finger toxins (3FTXs) are the most clinically relevant components in cobra (genus Naja) venoms. Administration of the antivenom is the recommended treatment for the snakebite envenomings, while the efficacy to cross-neutralize the different cobra ...
Bing-Sin Liu   +6 more
doaj   +2 more sources

A Rapid and International Applicable Diagnostic Device for Cobra (Genus Naja) Snakebites

open access: yesToxins, 2020
Cobra snakes (genus Naja) are some of the most dangerous snake species in Asia and Africa, as their bites cause severe life-threatening respiratory failure and local tissue destruction, especially in the case of late diagnosis. The differential diagnosis
Jing-Hua Lin   +3 more
doaj   +2 more sources

COBRA Frames: Contextual Reasoning about Effects and Harms of Offensive Statements [PDF]

open access: yesAnnual Meeting of the Association for Computational Linguistics, 2023
Warning: This paper contains content that may be offensive or upsetting. Understanding the harms and offensiveness of statements requires reasoning about the social and situational context in which statements are made.
Xuhui Zhou   +6 more
semanticscholar   +1 more source

Multi-Influenza HA Subtype Protection of Ferrets Vaccinated with an N1 COBRA-Based Neuraminidase

open access: yesViruses, 2023
The influenza neuraminidase (NA) is a promising target for next-generation vaccines. Protection induced by vaccination with the computationally optimized broadly reactive NA antigen (N1-I COBRA NA) was characterized in both influenza serologically naive ...
A. L. Skarlupka   +4 more
semanticscholar   +1 more source

Bivalent H1 and H3 COBRA Recombinant Hemagglutinin Vaccines Elicit Seroprotective Antibodies against H1N1 and H3N2 Influenza Viruses from 2009 to 2019

open access: yesJournal of Virology, 2022
Standard-of-care influenza virus vaccines are composed of a mixture of antigens from different influenza viral subtypes. For the first time, lead COBRA H1 and H3 HA antigens, formulated as a bivalent vaccine, have been investigated in animals with ...
James D. Allen, T. Ross
semanticscholar   +1 more source

Applicability of Industry 4.0 Technologies in the Reverse Logistics: A Circular Economy Approach Based on COmprehensive Distance Based RAnking (COBRA) Method

open access: yesSustainability, 2022
The logistics sector plays one of the most important roles in the supply chain with the aim of providing a fast, flexible, safe, economical, efficient, and environmentally acceptable performance of freight transport flows. In addition, the popularization
Mladen Krstić   +4 more
semanticscholar   +1 more source

Recent Advances in Catalytic and Technology-Driven Radical Addition to N,N-Disubstituted Iminium Species

open access: yesMolecules, 2023
Recently, radical chemistry has grown exponentially in the toolbox of organic synthetic chemists. Upon the (re)introduction of modern catalytic and technology-driven strategies, the implementation of highly reactive radical species is currently ...
Sylvain Oudeyer   +3 more
doaj   +1 more source

Current Insights in the Mechanisms of Cobra Venom Cytotoxins and Their Complexes in Inducing Toxicity: Implications in Antivenom Therapy

open access: yesToxins, 2022
Cytotoxins (CTXs), an essential class of the non-enzymatic three-finger toxin family, are ubiquitously present in cobra venoms. These low-molecular-mass toxins, contributing to about 40 to 60% of the cobra venom proteome, play a significant role in cobra
Bhargab Kalita, Y. Utkin, A. Mukherjee
semanticscholar   +1 more source

Continuous Flow Synthesis of Propofol

open access: yesMolecules, 2021
Herein, we report a continuous flow process for the synthesis of 2,6-diisopropylphenol—also known as Propofol—a short-acting intravenous anesthesia, widely used in intensive care medicine to provide sedation and hypnosis.
Romain Mougeot   +3 more
doaj   +1 more source

Local Cytotoxic Effects in Cobra Envenoming: A Pilot Study

open access: yesToxins, 2022
The cobra (genus Naja (N.)) is one of the most common venomous snakes. Due to its frequency and deadly complications of muscle paralysis, local necrosis, and chronic musculoskeletal disability, it should not be ignored.
Jing-Hua Lin   +3 more
semanticscholar   +1 more source

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