Results 11 to 20 of about 48,605 (285)

Bivalent H1 and H3 COBRA Recombinant Hemagglutinin Vaccines Elicit Seroprotective Antibodies against H1N1 and H3N2 Influenza Viruses from 2009 to 2019

Journal of Virology, 2022
Standard-of-care influenza virus vaccines are composed of a mixture of antigens from different influenza viral subtypes. For the first time, lead COBRA H1 and H3 HA antigens, formulated as a bivalent vaccine, have been investigated in animals with ...
James D. Allen, T. Ross
semanticscholar   +1 more source

Systematic Review and Meta-Analysis of the Association Between Subjective and Objective Cognitive Function in Mood Disorders. [PDF]

Bipolar Disord
ABSTRACT Introduction The association between subjective and objective cognitive function in mood disorders is hotly debated, particularly in the choice of outcomes to measure pro‐cognitive effects of interventions. We systematically reviewed the evidence regarding this association, including analysis of predicting or moderating factors.
Eggleston K, Miskowiak KW, Porter R, Frampton C, Douglas K.   +4 more
europepmc   +2 more sources

Biogeographical venom variation in the Indian spectacled cobra (Naja naja) underscores the pressing need for pan-India efficacious snakebite therapy

PLoS Neglected Tropical Diseases, 2021
Background Snake venom composition is dictated by various ecological and environmental factors, and can exhibit dramatic variation across geographically disparate populations of the same species.
R. R. Senji Laxme, Saurabh S. Attarde, Suyog Khochare, Vivek Suranse, G. Martin, N. Casewell, R. Whitaker, K. Sunagar   +7 more
semanticscholar   +1 more source

Current Insights in the Mechanisms of Cobra Venom Cytotoxins and Their Complexes in Inducing Toxicity: Implications in Antivenom Therapy

Toxins, 2022
Cytotoxins (CTXs), an essential class of the non-enzymatic three-finger toxin family, are ubiquitously present in cobra venoms. These low-molecular-mass toxins, contributing to about 40 to 60% of the cobra venom proteome, play a significant role in cobra
Bhargab Kalita, Y. Utkin, A. Mukherjee
semanticscholar   +1 more source

MEREC-COBRA APPROACH IN E-COMMERCE DEVELOPMENT STRATEGY SELECTION

Journal of process management and new technologies, 2022
The research objective of the paper is to propose a model, based on the Multiple-Criteria Decision-Making (MCDM) methods, that facilitates a selection process of an adequate strategy directed to the development of e-commerce.
G. Popović, Đorđe Pucar, F. Smarandache   +2 more
semanticscholar   +1 more source

Local Cytotoxic Effects in Cobra Envenoming: A Pilot Study

Toxins, 2022
The cobra (genus Naja (N.)) is one of the most common venomous snakes. Due to its frequency and deadly complications of muscle paralysis, local necrosis, and chronic musculoskeletal disability, it should not be ignored.
Jing-Hua Lin, Wang-Chou Sung, Han-Wei Mu, D. Hung   +3 more
semanticscholar   +1 more source

King Cobra and snakebite envenomation: on the natural history, human-snake relationship and medical importance of Ophiophagus hannah

Journal of Venomous Animals and Toxins including Tropical Diseases, 2022
King Cobra (Ophiophagus hannah) has a significant place in many cultures, and is a medically important venomous snake in the world. Envenomation by this snake is highly lethal, manifested mainly by neurotoxicity and local tissue damage. King Cobra may be
Choo Hock Tan, Aymeric Bourges, K. Y. Tan   +2 more
semanticscholar   +1 more source

A Sulfur Dioxide Covariance-Based Retrieval Algorithm (COBRA): application to TROPOMI reveals new emission sources

Atmospheric Chemistry and Physics, 2021
. Sensitive and accurate detection of sulfur dioxide (SO2) from space is important for monitoring and estimating global sulfur emissions. Inspired by detection methods applied in the thermal infrared, we present here a new scheme to retrieve SO2 columns ...
N. Theys, V. Fioletov, Can Li, I. de Smedt, C. Lerot, C. McLinden, N. Krotkov, D. Griffin, L. Clarisse, P. Hedelt, D. Loyola, T. Wagner, Vinod Kumar, A. Innes, Roberto Ribas, F. Hendrick, J. Vlietinck, H. Brenot, M. Van Roozendael   +18 more
semanticscholar   +1 more source

The Indian cobra reference genome and transcriptome enables comprehensive identification of venom toxins

Nature Genetics, 2020
Snakebite envenoming is a serious and neglected tropical disease that kills ~100,000 people annually. High-quality, genome-enabled comprehensive characterization of toxin genes will facilitate development of effective humanized recombinant antivenom.
Kushal Suryamohan, Sajesh P. Krishnankutty, Joseph Guillory, Matthew J. Jevit, Markus S. Schröder, Meng Wu, Boney Kuriakose, Oommen K. Mathew, R. C. Perumal, I. Koludarov, L. Goldstein, K. Senger, Mandumpala Davis Dixon, Dinesh Velayutham, Derek Vargas, Subhra Chaudhuri, Megha Muraleedharan, Ridhi Goel, Y. Chen, A. Ratan, Peter Liu, Brendan K. Faherty, Guillermo de la Rosa, H. Shibata, M. Baca, M. Sagolla, James Ziai, G. Wright, D. Vučić, Sangeetha Mohan, Aju Antony, Jeremy Stinson, D. Kirkpatrick, R. Hannoush, S. Durinck, Z. Modrusan, E. Stawiski, K. Wiley, T. Raudsepp, R. Kini, A. Zachariah, S. Seshagiri   +41 more
semanticscholar   +1 more source

A Neurotoxic Snake Venom without Phospholipase A2: Proteomics and Cross-Neutralization of the Venom from Senegalese Cobra, Naja senegalensis (Subgenus: Uraeus)

Toxins, 2021
The Senegalese cobra, Naja senegalensis, is a non-spitting cobra species newly erected from the Naja haje complex. Naja senegalensis causes neurotoxic envenomation in Western Africa but its venom properties remain underexplored.
K. Wong, K. Y. Tan, N. Tan, Choo Hock Tan   +3 more
semanticscholar   +1 more source